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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Satellite Ground Station Network for Real-Time Space Weather Data

    SBC: USML L.L.C.            Topic: 843W

    The goal of this Phase II effort is to carry out a series of tasks with the purpose of developing a ground station network that can provide less than 15 minute latency in acquiring data from NOAA space weather assets. These tasks include:  Finalize a set of specifications for ground stations so they can be used to determine the suitability of existing ground stations for the different missions ...

    SBIR Phase II 2017 Department of Commerce
  2. PLATFORM FOR NEUROCOGNITIVE EVALUATION AND MONITORING

    SBC: ENFORMIA INC.            Topic: NCI

    Current standardized neuropsychological tests are based on decades old paper and pencil methods They lack reliability sensitivity specificity repeatability and require trained neuropsychologists to administer them Their administration in clinical and research settings result in high cost complexity and inconsistent results There is a need and a commercial opportunity for an extensible co ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. An RNA targeted platform for anti flavivirus drug discovery

    SBC: Ribometrix LLC            Topic: NIAID

    SUMMARY Emerging and re emerging mosquito borne flaviviruses cause widespread mortality morbidity and economic burden Options for prevention and treatment of mosquito borne flaviviruses are limited Flavivirus vaccines face unique development challenges no antiviral therapies are available and the mosquito vectors have proven difficult to eradicate Despite vaccines against Yellow Fever and J ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Peptide based tool for the rapid isolation of quiescent monocytes from peripheral blood

    SBC: AFFINERGY, LLC            Topic: 102

    SUMMARY ABSTRACT Dendritic cell DC therapy represents a new and promising immunotherapeutic approach for treatment of advanced stage cancers with DC vaccines already approved for use in advanced prostate cancer and more than DC based vaccines in the clinical development pipeline for other cancers In particular the US market for cancer vaccines including DC based vaccines is set to expan ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Novel enzyme inhibitor screening platform using modified designer nucleosomes

    SBC: EPICYPHER, INC.            Topic: 300

    Project Summary Nucleosomes are the basic units of chromatin comprised of a histone octamer made up of two copies of each of the histone subunits H A H B H and H Changes in chromatin structure and function are mediated through histone post translational modifications PTMs such as methylation and ubiquitination Alterations of specific PTMs are highly associated with human diseases i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Practical Mass Spectrometry Upgrade for Identifying Fragile Protein Modifications by ECD

    SBC: E-Msion, Inc.            Topic: 400

    The speed resolution and high mass accuracy of modern mass spectrometers have revolutionized proteomics particularly for determining fragile post translational modifications that control most cellular processes Accurate identification and quantitation of phosphorylation sites remain a major challenge in proteomics The key weakness with mass spectrometry for phospho proteomics lies in the metho ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Microfluidic S nitrosothiol Sensor

    SBC: CLINICAL SENSORS, INC.            Topic: 400

    PROJECT SUMMARY This Small Business Innovation Research SBIR Phase I project aims to develop an accurate rapid and commercially available microfluidic sensor that measures low molecular weight S nitrosothiols in biological samples S nitrosothiols RSNOs the primary transporters of nitric oxide NO in physiology play a critical role for NOandapos s bioactivity Homeostatic control of low ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. High throughput screening of arrayed single cells for automated analysis of phenotypic heterogeneity

    SBC: Celldom, Inc.            Topic: 300

    ABSTRACT The overall objective of this SBIR Phase I proposal is to develop a high throughput screening platform that can analyze the phenotypic heterogeneity of single cells exposed to small molecule growth inhibitors To achieve this objective we will conduct the following specific aims demonstrate a commercially viable approach for rapidly organizing andgt single cells into an arra ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Training the brain with a robotic device for balance recovery in near frail older adults

    SBC: AMES TECHNOLOGY, INC.            Topic: NICHD

    DESCRIPTION provided by applicant The long term goal of this project is to reduce falls in older adults by improving their ability to recover equilibrium during a slip or trip The proposed strategy is to use AMES an FDA cleared non invasive intervention that has been shown to enhance motor performance in able bodied adults and to reduce sensorimotor impairment in both the upper and lower lim ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Dynamic Mining and Contextualization of the Scientific Literature This project creates interactive science articles and collects data metrics accelerating scientific discovery and reproducibility

    SBC: InSilico, Inc            Topic: 172

    The proposed Dynamic Mining and Contextualization of the Scientific Literature DMCSL provides an open lane of communication between authors science journals readers and databases The outcome of this communication portal will be a database containing mineable metadata for researchers reagent supply and biotech companies Data will be available to companies through individualized subscription ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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