You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    AbstractThe treatment of large cartilage lesions is a difficult clinical problem for which there are few good solutionsLeft untreatedthese lesions tend to degenerate to chronic pain and osteoarthritisOAultimately requiring a total joint replacementFor patients suffering from knee OAandin particularunicompartmental OAunicondylar knee arthroplastyUKAis an available first line treatment option that p ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. PLATFORM FOR NEUROCOGNITIVE EVALUATION AND MONITORING

    SBC: ENFORMIA INC.            Topic: NCI

    Current standardized neuropsychological tests are based on decades old paper and pencil methods They lack reliability sensitivity specificity repeatability and require trained neuropsychologists to administer them Their administration in clinical and research settings result in high cost complexity and inconsistent results There is a need and a commercial opportunity for an extensible co ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Discovery of inhibitors of Zika virus

    SBC: VENATORX PHARMACEUTICALS INC            Topic: NIAID

    PROJECT SUMMARY Novel inhibitors of Zika virusZIKVare urgently needed to prevent the occurrence of virus induced microcephaly and Guillain BarrsyndromeThe objective of this Phase I SBIR feasibility study is to identify drug like compounds that specifically inhibit ZIKV replicationDuring the course of this Phase I funding periodwe will execute hit finding campaign against a library ofcompounds with ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. An RNA targeted platform for anti flavivirus drug discovery

    SBC: Ribometrix LLC            Topic: NIAID

    SUMMARY Emerging and re emerging mosquito borne flaviviruses cause widespread mortality morbidity and economic burden Options for prevention and treatment of mosquito borne flaviviruses are limited Flavivirus vaccines face unique development challenges no antiviral therapies are available and the mosquito vectors have proven difficult to eradicate Despite vaccines against Yellow Fever and J ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A Rapid Low Cost Point of Care Diagnostic for detection of Zika virus RNA

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    ABSTRACT Zika virus ZIKV has rapidly emerged and spread through South and Central America the Caribbean and Puerto Rico since its last outbreak in Micronesia in Transmitted by the mosquito Aedes sp its forecasted spread will have a major impact on the Southeast U S Most ZIKV infections remain asymptomatic or present with non specific rash and fever therefore they have been difficult ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Development of user-friendly fluorescence based assays for marine toxins

    SBC: SEATOX RESEARCH INC            Topic: 113

    ABSTRACTHarmful algal bloomsHABsare becoming frequent occurrences off the coasts of the United Stateswith specific instances in the coastal waters of the west coastthe Gulf of Mexicoand the Pacific OceanHistoricallyHABs have been associated with fish kills and marine mammal mortalitieshowevertheir effects on human health and economic loss due to HAB contamination of seafood are becoming more preva ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Peptide based tool for the rapid isolation of quiescent monocytes from peripheral blood

    SBC: AFFINERGY, LLC            Topic: 102

    SUMMARY ABSTRACT Dendritic cell DC therapy represents a new and promising immunotherapeutic approach for treatment of advanced stage cancers with DC vaccines already approved for use in advanced prostate cancer and more than DC based vaccines in the clinical development pipeline for other cancers In particular the US market for cancer vaccines including DC based vaccines is set to expan ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A low cost automated Gallium drug preparation device for diagnostic PET imaging

    SBC: Five Eleven Pharma Inc.            Topic: 102

    Abstract Five Eleven Pharma is developing a simple low cost device for automating the preparation of Ga labeled drugs at any site that is performing PET imaging The device is being developed to support the broader creation distribution research and use of Ga compounds in diagnostic PET imaging There has been a surge in the use of Ga based radiopharmaceuticals throughout the world in ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Novel enzyme inhibitor screening platform using modified designer nucleosomes

    SBC: Epicypher, Inc.            Topic: 300

    Project Summary Nucleosomes are the basic units of chromatin comprised of a histone octamer made up of two copies of each of the histone subunits H A H B H and H Changes in chromatin structure and function are mediated through histone post translational modifications PTMs such as methylation and ubiquitination Alterations of specific PTMs are highly associated with human diseases i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Microfluidic S nitrosothiol Sensor

    SBC: CLINICAL SENSORS, INC.            Topic: 400

    PROJECT SUMMARY This Small Business Innovation Research SBIR Phase I project aims to develop an accurate rapid and commercially available microfluidic sensor that measures low molecular weight S nitrosothiols in biological samples S nitrosothiols RSNOs the primary transporters of nitric oxide NO in physiology play a critical role for NOandapos s bioactivity Homeostatic control of low ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government