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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Clinical Development of a Therapeutic Agent for COPD


    DESCRIPTION provided by applicant Hypersecretion of mucus into the respiratory airways is a major contributing factor in several lung diseases including chronic pulmonary disease COPD asthma cystic fibrosis allergic rhinitis and bronchiectasis Despite the obvious medical importance there presently are no effective therapies to control excess mucus secretion in these diseases and very ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Improved diagnostic and monitoring assays for thyroid cancer

    SBC: Soymeds Inc            Topic: NCI

    DESCRIPTION provided by applicant Thyroid cancer is the most common type of endocrine malignancy New thyroid cancers patients are identified daily and most patients live for decades following diagnosis Thyroglobulin TG levels in the sera or in fine needle biopsies of thyroid cancer patients are routinely quantified using various agency approved e g FDA immunoassays for diagnostic and p ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Manufacturing Processes for Tissue Engineered Vascular Grafts

    SBC: HUMACYTE, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant This Phase IIB SBIR application is responsive to NHLBI RFA HL andquot NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart Lung Blood and Sleep Disorders and Diseases R andquot This RFA solicits work on andquot basic applied and clinical research on all product and service development related to the ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health

    SBC: Innovation Research And Training, Inc.            Topic: NICHD

    Adolescents with Fetal Alcohol Spectrum Disorder FASD are at risk for substance use and abuse Given the dearth of interventions designed specifically for adolescents with FASD there exists a need for evidence based preventive intervention programs for this population Thus the goal of the proposed Phase II application is to complete the product development and evaluate the effectiveness of t ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Porous Membrane Electrode for Quantitative Detection of Toxins

    SBC: Mercury Science Inc.            Topic: 816N

    In Phase I, a novel porous electrode was designed to demonstrate a rapid, simple assay for the detection of domoic acid in marine samples. During Phase II, methods to manufacture porous electrodes will be improved to enable high volume production of low-cost biosensors that can be connected to a potentiostat. These biosensors will be incorporated into a portable test kit for the quantitation of do ...

    SBIR Phase II 2013 Department of CommerceNational Oceanic and Atmospheric Administration
  6. User-Friendly 3D Environmental Profiler AUV

    SBC: NEKTON RESEARCH LLC            Topic: 813

    We propose Ranger ES, a low cost, autonomous underwater vehicle (AUV) for three-dimensional profiling and water samplings of chemical, physical, and biological parameters of oceanic and fresh waters. The AUV will be programmable by point and click to analyze a volume of water continuously for the selected parameters. After returning for pickup after a day¿s run, it will download its data into a ...

    SBIR Phase I 2006 Department of Commerce
  7. Construction of a Force Probe for Characterization of Microscale Features

    SBC: INSITUTEC, INC.            Topic: N/A

    The Phase 2 objective is to provide NIST with a modular gauge head unit equipped with InsituTec's standing wave probe technology. The complete gauge head unit will be retrofitted to the NIST M48 which is one of the most precise measuring machines in the world. This unit will enable NIST to achieve the agency's program goal in dimensional metrology which is to provide microscale measurement capacit ...

    SBIR Phase II 2006 Department of CommerceNational Institute of Standards and Technology

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