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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Delivery of pathogen trapping antibodies for vaginal protection

    SBC: MUCOMMUNE, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Despite immense efforts in behavioral interventions to promote safer sexual practices sexually transmitted infections STIs continue to be a pandemic worldwide Unfortunately there are no effective vaccines or microbicides for the majority of STIs A pathogen specific safe effective and discreet vaginal microbicide that does not require daily or sex associ ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. New Class of Bright Sharp Tunable Near Infrared Fluorophores for Flow Cytometry

    SBC: Nirvana Sciences, Inc.            Topic: R

    DESCRIPTION provided by applicant Polychromatic flow cytometry FC is one of the most powerful analytical techniques routinely used by both basic research and clinical diagnostics laboratories for the immunological categorization of cells Dyes used for FC typically exhibit broad fluorescent emission bands with full width at half maximum fwhm values of nm This limits the maximum numbe ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. The CellRaft AIR System Workflow Automation for Stem Cell Isolation and Recovery

    SBC: Cell Microsystems, Inc.            Topic: 200

    DESCRIPTION provided by applicant Stem cell research is an emerging field with the promise of creating dramatic new approaches for disease treatment and drug discovery The research and regenerative medicine market space for stem cells is one of the most dynamic areas in the life science industry today Globally the stem cell market is growing at a CAGR of and will reach an approximate ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Innovating Tablet Based Cognitive Assessment for CNS Disorders of Aging

    SBC: NEUROCOG TRIALS            Topic: NIA

    DESCRIPTION provided by applicant Aging populations have become a key target for therapeutics developers particularly for indications impacting cognitive function Conditions such as Alzheimerandapos s disease and vascular dementia affect the quality of life of aging Americans largely due to their impact on cognitive function with insufficient therapeutic options Recent reports indicate tha ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Internally Calibrated Chromatin Immunoprecipitation Using Barcoded Nucleosomes

    SBC: EPICYPHER, INC.            Topic: 172

    DESCRIPTION provided by applicant Chromatin immunoprecipitation ChIP is one of the core methods in the study of epigenetic regulation of gene expression Analytical methods such as qPCR microarray and next generation sequencing NGS have increased throughput but not the reliability of ChIP datasets Using state of the art reagents ChIP is at best semi quantitative and at worst unreprese ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Software for Dynamic Behavioral Outcomes PORTAL and Dashboard

    SBC: Health Outcomes Inc            Topic: 104

    DESCRIPTION provided by applicant In his directorandapos s blog Dr Insel Director of NIMH described new directions for research andquot W e need to stop thinking about moving research to practice and start thinking about moving practice to research The idea is simple understand what works in the real world of practice by using scientific methods like randomization and statistical comp ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. e Unstuck Interactive e learning software for parents to support executive functioning and behavior regulation in children with Autism Spectrum Disorder

    SBC: 3-C Institute for Social Development, Inc.            Topic: 103

    DESCRIPTION provided by applicant The current prevalence of Autism Spectrum Disorder is in children and of these children do not have an intellectual disability ASDwoID Individuals with ASDwoID are at considerable risk for maladaptive adult outcomes e g un or underemployment and executive functioning EF impairments significantly contribute to this risk Unstuck and On Targe ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Enhancing Research Capacity via Developmentally Appropriate Online Data Collection System

    SBC: 3-C Institute for Social Development, Inc.            Topic: 100

    DESCRIPTION provided by applicant Data collection for clinical behavioral and social research has traditionally been accomplished via paper and pencil forms collected in person by telephone or through the mail however recent technological advances have resulted in a multitude of online data collection systems DCS that deploy measures and collect data online More than of all data co ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Simple Self Contained Self Sterilizing Bag

    SBC: Brighton Development            Topic: NCATS

    DESCRIPTION provided by applicant The safe and simple self sterilizing pouch system with its INNOVATIVE sterilant releasing plastic insert is ideal for STERILIZATION of all medical items especially heat and moisture sensitive medical products The product has numerous applications both commercially as well as hospital and in home healthcare applications Virtually any heat source can be use ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Nomethiazoles harnessing GABA and NO mimetic activity for Alzheimer s therapy

    SBC: sGC Pharma Inc.            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD occurs in one out of eight Americans of age and affects of the elderly over Current FDA approved drugs provide short term symptomatic relief of AD There is a pressing need to discover new disease modifying medications AD is multifactorial in origin and progression A drug attenuating several underlying factors is a p ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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