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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: Qatch Technologies, LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  3. Measuring the Concentration of Host-cell Proteins in Biomanufacturing Using Silicon Nanowire Array Sensors

    SBC: Advanced Silicon Group            Topic: NA

    Our innovation is a low cost, sensitive, quantitative biosensor that can detect many biomarkers on the same chip. Our sensor consists of vertically aligned silicon nanowires. The silicon nanowires’ high surface area to volume ratio makes them sensitive to the environment around them and can thus lead to high sensitivity detection. Each of the nanowires can be functionalized to be sensitive to ei ...

    SBIR Phase I 2018 Department of CommerceNational Institute of Standards and Technology
  4. Riptide Hypoxic Zone AUV

    SBC: Riptide Autonomous Solutions, LLC            Topic: 827

    TECHNICAL ABSTRACT: Buoyancy driven oceanographic gliders, although reasonably cost effective, have challenges operating in the zones due to high gradients in water density. Under this topic, Riptide will provide a cost-effective autonomous undersea vehicle (AUV) design leveraged from Riptide's family of man-portable AUVs that can more effectively map the hypoxic areas. The stated goals of this to ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  5. Harmful Algal Bloom Species, Toxin and Total Phytoplankton Identification System (HABStats) for HandHeld, Remotely Networked or Submersible Operation

    SBC: CoastalOceanVision, Inc            Topic: 821

    TECHNICAL ABSTRACT: We propose to develop and commercialize the next generation of low cost, low power, ruggedized, and accurate phytoplankton single cell and whole colony counting, characterization and classification system called HABStats. We will accomplish this using the following three unique and innovative approaches: 1) High-throughput color, Light Field Imaging Flow Cytometry to acquire mo ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  6. Low-cost Mooring Location Beacon for Coastal Applications

    SBC: Triton Systems, Inc.            Topic: 825

    TECHNICAL ABSTRACT: Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with mini ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Developing a robust and scalable calibration approach to low-cost AQ sensing

    SBC: Aerodyne Research, Inc.            Topic: 813

    TECHNICAL ABSTRACT: Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring inexpensive and widespread. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack o ...

    SBIR Phase I 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Automated peak fitting and analysis software for advanced gas chromatography and mass spectrometer systems

    SBC: Aerodyne Research, Inc.            Topic: 827

    TECHNICAL ABSTRACT: Recent advances in gas chromatographic (GC) and mass spectrometric (MS) techniques for atmospheric measurements have led to highly complex data sets that have overwhelmed the capabilities of current data analysis software. We propose a new method for the automated reduction of chromatographic data using peak-fitting algorithms. By relying upon constrained peak-fit parameterizat ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Development of a Portable 3-dimensional Variational (3DVAR) Data Assimilation Module for NOAA Operational Forecasting Systems

    SBC: REMOTE SENSING SOLUTIONS, INC.            Topic: 814

    TECHNICAL ABSTRACT: We propose to continue the development of a generalized 3DVAR data assimilation module, in an open-source and non-proprietary programming language, which is compatible with FVCOM and incorporated into the Lake Erie Operational Forecast System (LEOFS). We will leverage our experience and expertise in using 3DVAR for a ROMS-based real-time forecast system for the California coast ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration
  10. Automated HCl laser monitor for long term and flight deployments

    SBC: Aerodyne Research, Inc.            Topic: 813

    TECHNICAL ABSTRACT: Tropospheric oxidation capacity is dominated by HOx photochemistry, however halogen atoms and oxides significantly affect these chemical cycles. A sensitive and robust measurement of gaseous HCl is critically important to improve our understanding of halogen chemistry and its impacts on the spatial and temporal oxidation capacity of the atmosphere. In Phase I, we met all of our ...

    SBIR Phase II 2018 Department of CommerceNational Oceanic and Atmospheric Administration

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