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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: Qatch Technologies, LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  3. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: Zymeron Corporation            Topic: CBD181004

    Given the unforeseen/unanticipated use of nerve agents in the battlefield and on the homeland, military personnel can benefit from this oncedaily pretreatment. It may also be desirable to pretreat certain medical and emergency aid personnel following a known/suspected nerveagent attack. Also, a novel, improved PB extended release formulations can be commercialized for the treatment of myasthenia g ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Dual Formulation of Atropine and Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survivalrates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ca ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Durable Stretch Barrier Materials

    SBC: LaunchBay LLC            Topic: CBD181003

    Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders asthe first line of defense for personnel working in contaminated environments. Many innovative products have been developed for thechemical protective clothing market in response to demand from the market place for improved performance. However, the need forte ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  6. Open-Path Spatial Ring Down Spectrometer for Chemical Vapor Detection

    SBC: Physical Sciences Inc.            Topic: CBD171004

    Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  7. NANOMETER-SIZE STEP HEIGHT TEST STRUCTURES

    SBC: Advanced Technologies/Laboratories Intl            Topic: N/A

    MCNC PROPOSES A FEASIBILITY STUDY AND EVALUATION OF THREE PROMISING APPROACHES TO THE FABRICATION OF SURFACE TEST STRUCTURES ON SILICON. SURFACE FEATURES ON THE FIRST STRUCTURE WILL BE PRODUCED BY CONTROLLABLY ETCHING THERMALLYGROWN OXIDES. FEATURES ON THE SECOND WILL BE MADE BY ETCHING PIEZOELECTRIC THIN FILMS. USING THE PIEZOELECTRIC FILM AS PART OF A CAPACITOR, STEP-HEIGHT CAN BE VARIED AND PRO ...

    SBIR Phase I 1992 Department of Commerce
  8. SATELLITE IMAGERY COMPRESSION

    SBC: Alden Electronics Inc            Topic: N/A

    THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP DATA COMPRESSIONTECHNIQUES USED TO COMPRESS DIGITAL ENVIRONMENTAL SATELLITE DATA FROM THE NATIONAL CLIMATIC DATA CENTER (NCDC) ARCHIVES SUCH THAT THE RESULTING DATA CAN BE READILY USED WITHIN THE LIMITED RESOURCES OF PC/AT SYSTEMS. THE JOINT PHOTOGRAPHIC EXPERTS GROUP (JPEG) HAS DEVELOPED ANINTERNATIONAL STANDARD FOR THE COMPRESSION OF CONTINUOUS TONE DI ...

    SBIR Phase I 1992 Department of Commerce
  9. TRACS- TOOLKIT FOR RECOGNITION AND AUTOMATIC CLASSIFICATIONOF SOLAR FEATURES

    SBC: AMERINEX APPLIED IMAGING, INC.            Topic: N/A

    N/A

    SBIR Phase I 1992 Department of Commerce
  10. ON-BOARD PROCESSING OF DOGFISH AND SKATES

    SBC: Fisherman Joint Venture            Topic: N/A

    THE DECLINE IN THE NEW ENGLAND (NE) GROUND FISH STOCK IS SEVERELY AFFECTING THE NE FISHERIES' ECONOMY. TO REVERSE THIS DESTRUCTIVE TREND, NMFS HAS THE DIFFICULT AND UNPOPULARTASK OF IMPLEMENTING STOCK RECOVERY PROGRAMS WHICH REQUIRE CATCH REDUCTIONS. NMFS REPORTS 70% OF PRESENT FISH STOCKS ARE DOGFISH AND SKATES WHICH ARE UNDER-UTILIZED AND ARE GROUND FISH PREDATORS. ALTHOUGH THESE ABUNDANT FISH H ...

    SBIR Phase II 1992 Department of Commerce

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