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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: Qatch Technologies, LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  3. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: Zymeron Corporation            Topic: CBD181004

    Given the unforeseen/unanticipated use of nerve agents in the battlefield and on the homeland, military personnel can benefit from this oncedaily pretreatment. It may also be desirable to pretreat certain medical and emergency aid personnel following a known/suspected nerveagent attack. Also, a novel, improved PB extended release formulations can be commercialized for the treatment of myasthenia g ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Dual Formulation of Atropine and Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survivalrates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ca ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Durable Stretch Barrier Materials

    SBC: LaunchBay LLC            Topic: CBD181003

    Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders asthe first line of defense for personnel working in contaminated environments. Many innovative products have been developed for thechemical protective clothing market in response to demand from the market place for improved performance. However, the need forte ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  6. Open-Path Spatial Ring Down Spectrometer for Chemical Vapor Detection

    SBC: Physical Sciences Inc.            Topic: CBD171004

    Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  7. Large Area Time-of-Flight Detectors for Imaging Science

    SBC: NOVA SCIENTIFIC INCORPORATED            Topic: 17b

    NOVA Scientific, Inc. proposes a Phase I SBIR program to develop, refine, and ultimately to commercialize, a large format 15 cm x 15 cm solid-state cold, thermal, and epithermal neutron imaging detector based on microchannel plates (MCPs). The imaging detector will be fabricated in a self-contained, hermetically sealed image tube, which does not require active vacuum pumping. This large area time- ...

    SBIR Phase I 2019 Department of Energy
  8. A Novel Catalytic Reactor For Conversion Of CO2 Into Benzene

    SBC: Susteon Inc.            Topic: 22c

    Almost 15 million metric tons per year of essentially pure CO2 is captured in the United States from ethanol, hydrogen, ammonia, and natural gas processing plants. Some of this CO2 is used for merchant applications such as food and beverage and other applications, but a large portion of this captured CO2 is emitted to the atmosphere. This CO2 can be converted into high value chemicals, but the key ...

    SBIR Phase I 2019 Department of Energy
  9. Ultra-low Temperature Cryostat for Application of High Electric Field in a Neutron Beam

    SBC: Janis Research Company, LLC            Topic: 17a

    Janis Research Company LLC proposes to develop an ultra-low temperature system with operation temperatures below 0.4 Kelvin and sample measurement capabilities for application of a high voltage up to 5kV. Upon further integration with an external magnetic field, this will be a unique ultra-low temperature platform to investigate the phases of multi-ferroic quantum materials and materials near a qu ...

    SBIR Phase I 2019 Department of Energy
  10. Large-area Radiation-hard Synchrotron X-ray Detectors

    SBC: CAPESYM, INC            Topic: 14a

    Modern synchrotron-based X-ray imaging techniques, such as coherent X-ray diffraction imaging and phase contrast imaging require high beam coherence and highly penetrating X-rays. The new generation of synchrotrons achieve enhanced coherence at beam energies greater than 30-50keV. These new prospects for non-destructive imaging require high spatial resolution and efficient large area detectors. Cu ...

    SBIR Phase I 2019 Department of Energy

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