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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Open-Path Spatial Ring Down Spectrometer for Chemical Vapor Detection

    SBC: PHYSICAL SCIENCES INC.            Topic: CBD171004

    Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: QATCH TECHNOLOGIES LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: ADVANCED SILICON GROUP, INC.            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  4. Developing a robust and scalable calibration approach to low-cost AQ sensing

    SBC: AERODYNE RESEARCH INC            Topic: 813

    Poor air quality represents a major public health risk, contributing to an estimated one of every eight deaths worldwide. Low-cost air quality sensors have developed rapidly over the last few years and offer the opportunity to make air quality monitoring widespread at an affordable price. However, low-cost sensors are currently unable to deliver accurate, reliable data due to a lack of understandi ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  5. OpenORB Low-Cost Mooring Location Beacon for Costal Applications

    SBC: TRITON SYSTEMS, INC.            Topic: 825

    Triton Systems, Inc. proposes development of the Open-Source Oceanographic Asset Recovery Beacon (OpenORB) that will allow the deployment of coastal instrumentation moorings with affordable protection against loss. This open-source kit would significantly reduce the purchase price of a commercial location beacon by allowing the end-user to assemble a customized system with minimal time and effort. ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  6. A Blubber or Dorsal Fin Piercing Tag Attachment System for Remotely-Deployed Cetacean Tags

    SBC: American Benchmark Machine Works            Topic: 824

    Animal-borne electronic instruments (tags) are critical tools for monitoring the behavior and ecology of cetaceans, providing data needed for managing their populations and mitigating the threats they face. Although remote-deployment of tags onto cetaceans that cannot be captured has provided valuable data, attachment durations have been frustratingly short and variable. Our Phase II goal is to de ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Durable Stretch Barrier Materials

    SBC: LaunchBay LLC            Topic: CBD181003

    Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders as the first line of defense for personnel working in contaminated environments. Many innovative products have been developed for the chemical protective clothing market in response to demand from the market place for improved performance. However, the need for ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  8. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: ZYMERON CORP            Topic: CBD181004

    Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  9. Dual Formulation of Atropine and Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and 2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survival rates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  10. Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    SBC: CMC PHARMACEUTICALS INC            Topic: CBD181005

    CMC Pharmaceuticals, Inc. (Cleveland, OH) is proposing developing a stable, combination product of two small molecule drug candidates as a counter measure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacological profiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
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