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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: Zymeron Corporation            Topic: CBD181004

    Given the unforeseen/unanticipated use of nerve agents in the battlefield and on the homeland, military personnel can benefit from this oncedaily pretreatment. It may also be desirable to pretreat certain medical and emergency aid personnel following a known/suspected nerveagent attack. Also, a novel, improved PB extended release formulations can be commercialized for the treatment of myasthenia g ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. Dual Formulation of Atropine and Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survivalrates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ca ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Durable Stretch Barrier Materials

    SBC: LaunchBay LLC            Topic: CBD181003

    Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders asthe first line of defense for personnel working in contaminated environments. Many innovative products have been developed for thechemical protective clothing market in response to demand from the market place for improved performance. However, the need forte ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Open-Path Spatial Ring Down Spectrometer for Chemical Vapor Detection

    SBC: Physical Sciences Inc.            Topic: CBD171004

    Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  6. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: Qatch Technologies, LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  7. IR Polarimetric Ocean Sensing Imager

    SBC: Aerodyne Research, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1999 Department of Commerce
  8. Advanced Absolute Radiometers Using Superconducting Transition Thermometers

    SBC: CAMBRIDGE RESEARCH AND INSTRUMENTATION            Topic: N/A

    Not Available In our Phase 1 work we were able to replicate and build on recent results at NIST with superconducting transition (SCT) thermometers, which suggested that dramatic improvements may be achieved in detectivity and range of application, of cryogenic electrical substitution radiometers. Cryo-ESR's are widely used as the most accurate absolute standards of radiative flux and irradiance. I ...

    SBIR Phase II 1999 Department of Commerce
  9. Device for the Uncontaminated Collection of Multiple Microbial Samples

    SBC: Mclane Research Laboratories,            Topic: N/A

    Not Available The objective of this research project is the development of an Autonomous Microbial Sampler (AMS) that will obtain uncontaminated and exogenous DNA-free microbial samples from deep-sea hydrothermal vents and other aquatic ecosystems. Sampling with the AMS may be conducted using manned submersibles, Remotely Operated Vehicles (ROV), Autonomous Underwater Vehicles (AUV) or during hydr ...

    SBIR Phase II 1999 Department of Commerce
  10. Novel Fiber Networked Diod Laser-Based Fire Detection

    SBC: Physical Sciences Inc.            Topic: N/A

    N/A

    SBIR Phase I 1999 Department of Commerce

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