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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: Qatch Technologies, LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Developing Silicon Nanowire Sensors to Measuring Host-Cell Proteins at a Biomanufacturing Line

    SBC: Advanced Silicon Group            Topic: None

    Our biosensor is made of silicon nanowire arrays functionalized with antibodies to measure the concentration of specific proteins. In this grant we will take a sensor that has been demonstrated for use in measuring a set of generic host cell proteins and we will apply the sensor to measure a set of proteins for a specific cell line. In doing so, we will demonstrate the utility of our sensor to be ...

    SBIR Phase II 2019 Department of CommerceNational Institute of Standards and Technology
  3. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: Zymeron Corporation            Topic: CBD181004

    Given the unforeseen/unanticipated use of nerve agents in the battlefield and on the homeland, military personnel can benefit from this oncedaily pretreatment. It may also be desirable to pretreat certain medical and emergency aid personnel following a known/suspected nerveagent attack. Also, a novel, improved PB extended release formulations can be commercialized for the treatment of myasthenia g ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Dual Formulation of Atropine and Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survivalrates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ca ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Durable Stretch Barrier Materials

    SBC: LaunchBay LLC            Topic: CBD181003

    Chemical, Biological, Radioactive and Nuclear (CBRN) protective ensembles are widely used by the US Military and civilian first responders asthe first line of defense for personnel working in contaminated environments. Many innovative products have been developed for thechemical protective clothing market in response to demand from the market place for improved performance. However, the need forte ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  6. Open-Path Spatial Ring Down Spectrometer for Chemical Vapor Detection

    SBC: Physical Sciences Inc.            Topic: CBD171004

    Physical Science Inc. (PSI) will develop a new approach to chemical vapor detection based on a novel open-path sample cell design. The PhaseI system level model predicts SNR supporting a probability of detection of 95% and a MTBFA of 168 hours for all relevant CWAs and TICs at the10 minute negligible MEG level at a 20 s measurement time. In addition to robust detection, the system design can provi ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  7. Ground-based Water Vapor Profiling Lidar

    SBC: Bennett Aerospace, Inc.            Topic: 832

    The objective of Phase II is to continue our efforts from the Phase I project and perform in-depth testing of technologies critical to achieving the required level of measurement performance. The Phase II project will involve the design of the NOAA water vapor profiling lidar and testing of component parts, seeking external sources of funding for the systems (for Phase III) and further creati ...

    SBIR Phase II 2010 Department of Commerce
  8. Efficient Extraction of Oil from Microalgae

    SBC: TIAX LLC            Topic: 815

    Microalgae are a promising feedstock for biofuels because of their high oil content, excellent CO2 capture, and ability to use brackish water and non-arable land. The extraction of oil from algae represents a challenging cost barrier to commercial biofuel production. Conventional technologies for algal oil extraction are energy-inefficient, cost-intensive, or non scalable, leading to bar ...

    SBIR Phase I 2010 Department of Commerce
  9. High Speed and High Sensitivity Quadrant Photo Detector

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    To further advance the characterization and utility of microcantilevers, next generation optical detectors with higher frequency response, improved displacement resolution and lower noise for weak signal detection are needed. Consequently, Radiation Monitoring Devices, Inc. (RMD) will develop a turnkey optical detector module for use in characterizing the displacement and resonant frequencies of m ...

    SBIR Phase I 2010 Department of CommerceNational Institute of Standards and Technology
  10. Sensor Systems for Complete Residential Energy Monitoring

    SBC: TIAX LLC            Topic: N/A

    In Phase 1, TIAX developed and demonstrated a residential energy monitoring system (R-EMS) with potential national energy savings of $20 billion annually. Based on user requirements and well-established systems engineering methodology, TIAX’s R-EMS solution is inexpensive, easy to install and operate, and is supportive of intuitive decision making about energy usage. In Phase 2, TIAX will ex ...

    SBIR Phase II 2010 Department of CommerceNational Institute of Standards and Technology

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