Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD Research Corporation            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD Research Corporation            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  3. NANOMETER-SIZE STEP HEIGHT TEST STRUCTURES

    SBC: Advanced Technologies/Laboratories Intl            Topic: N/A

    MCNC PROPOSES A FEASIBILITY STUDY AND EVALUATION OF THREE PROMISING APPROACHES TO THE FABRICATION OF SURFACE TEST STRUCTURES ON SILICON. SURFACE FEATURES ON THE FIRST STRUCTURE WILL BE PRODUCED BY CONTROLLABLY ETCHING THERMALLYGROWN OXIDES. FEATURES ON THE SECOND WILL BE MADE BY ETCHING PIEZOELECTRIC THIN FILMS. USING THE PIEZOELECTRIC FILM AS PART OF A CAPACITOR, STEP-HEIGHT CAN BE VARIED AND PRO ...

    SBIR Phase I 1992 Department of Commerce
  4. DIGESTIVE ENZYME SUPPLEMENTS TO INERT FEEDS FOR SMALL-EGG FISH LARVAE

    SBC: International Aquaculture Res            Topic: N/A

    INADEQUATE STARTER FEEDS SEVERELY HOLD BACK NEW AQUACULTURE ENTERPRISES SUCH AS PRESENT ATTEMPTS TO RAISE FISHES WHOSE LARVAE DEVELOP FROM SMALL EGGS AND HAVE VERY "DIFFICULT" FOOD REQUIREMENTS. INERT LARVAL FEEDS HAVE NOT SUCCESSFULLYELIMINATED THE STRICT DEPENDENCY ON NATURAL FORAGE DURING THE CRITICAL POST-LARVAL STAGE AFTER YOLK ABSORPTION AND BEFORE THE DEVELOPMENT OF A DIGESTIVE SYSTEM WITH ...

    SBIR Phase I 1987 Department of Commerce
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