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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  2. Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  3. High Char Yield Multifunctional Textile Finishes

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: N/A

    A need exists for advances in non toxic treatments for cover and barrier fabrics. Since polybrominated materials have been banned in many European countries and the production of a number of brominated additives terminated in the U.S. as well, future technologies must focus on non-halogenated treatments. In general, non-halogenated treatments (phosphates and borates) are not durable to aqueous sol ...

    SBIR Phase I 2010 Department of CommerceNational Institute of Standards and Technology
  4. Low/No Power Detector for Organophosphate Nerve Agents

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD10101

    Organophosphate (OP) nerve agents are the most dangerous chemical warfare agents and therefore pose a significant threat. Rapid and exact identification of the OP agent involved in any hazardous material incident could significantly facilitate the administration of the most effective therapeutic and allow for appropriate measures of protection and decontamination, thereby increasing survival of t ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  5. Residual Life Indicator for Adsorptive and Reactive Single-Pass Filtration Systems

    SBC: MORPHIX TECHNOLOGIES, INC.            Topic: CBD10106

    In peacetime environments, concerns over improbable encounter with agent threats are supplanted by the need to understand and assess the performance status or residual life (RL) capacity of sorbent-based technologies used in Collective Protection (ColPro) systems. Systems such as the M98 and M48A1 run continuously and therefore sample large volumes of outside air over their lifetime. It is well- ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  6. DEVELOPMENT OF A BIOSENSOR NANOFLUIDIC PLATFORM FOR INTEGRATION WITH TERAHERTZ SPECTROSCOPIC SYSTEM

    SBC: VIBRATESS            Topic: CBD10110

    The goal of this SBIR project is to develop and demonstrate an electrokinetically driven nanofluidic sensor device of the physical size and shape that will allow integration with a THz spectroscopic instrument. The substrate and channel surfaces within the device will be appropriate for the acquisition of THz-frequency spectroscopic features from bio-molecules (e.g., DNA, RNA, proteins) in soluti ...

    SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
  7. Traffic Intersection Simulation of IntelliDrive, J2735, and DSRC/WAVE with eTEXAS

    SBC: HARMONIA HOLDINGS GROUP, LLC            Topic: 101FH3

    Harmonia’s proposed work will be instrumental in accelerating the maturity of IntelliDrive applications that avoid intersection collisions. This proposal unlocks the storehouse of modeling detail in TEXAS under the cost-free GPL copyleft license to organizations building IntelliDrive applications for collision avoidance at intersections. We add SAE J2375 sPAT messages reporting traffic signal ...

    SBIR Phase I 2010 Department of Commerce
  8. Construction of a Force Probe for Characterization of Microscale Features

    SBC: INSITUTEC, INC.            Topic: N/A

    The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...

    SBIR Phase I 2005 Department of CommerceNational Institute of Standards and Technology
  9. Handheld Photoacoustic Chemical Agent and Toxic Industrial Material Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  10. Cost-Effective Manufacturing of a Novel Selective Algaecide for the Fresh-Water Aquaculture Industry

    SBC: Nature Diagnostics, Inc.            Topic: 815

    The cost-effective manufacturing of a novel algaecide against blue green algae in fresh-water aquaculture operations has great potential for controlling ¿off-flavor¿ problems in pond-raised catfish. The proposed natural-based algaecide has selective activity for blue-green algae as well as a more favorable environmental performance profile with little/no activity towards complimentary phytoplan ...

    SBIR Phase I 2005 Department of Commerce
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