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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: QATCH TECHNOLOGIES LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Nanomachine Device for Semiconductor Process Control Monitoring

    SBC: XALLENT INC.            Topic: None

    Conventional characterization and test methods are increasingly ineffective when applied to structures less than 100 nanometers, causing challenges across R&D, process control and failure analysis. An increasing number of subtle defects become prominent drivers of failure as device size and operating margins decrease, e.g., processing anomalies in thin gate oxides, substrate problems related to do ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  3. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: ZYMERON CORP            Topic: CBD181004

    Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Construction of a Force Probe for Characterization of Microscale Features

    SBC: INSITUTEC, INC.            Topic: N/A

    The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...

    SBIR Phase I 2005 Department of CommerceNational Institute of Standards and Technology
  5. Handheld Photoacoustic Chemical Agent and Toxic Industrial Material Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  6. 3D Scaffold and Stem Cell Based Bioengineered Skin for Treatment of Cutaneous Vesicant Injury

    SBC: Nomadics, Inc.            Topic: CBD05117

    Vesicants have been used as chemical warfare agents since World War I and are still considered a major class of chemical threat agents both for the military and for homeland security. There are four different vesicating agents: impure sulfur mustard, distilled sulfur mustard, phosgene oxime, and lewisite. Among them, mustard is the most important militarily. The organs most commonly affected by ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  7. NANOMETER-SIZE STEP HEIGHT TEST STRUCTURES

    SBC: Advanced Technologies/Laboratories Intl            Topic: N/A

    MCNC PROPOSES A FEASIBILITY STUDY AND EVALUATION OF THREE PROMISING APPROACHES TO THE FABRICATION OF SURFACE TEST STRUCTURES ON SILICON. SURFACE FEATURES ON THE FIRST STRUCTURE WILL BE PRODUCED BY CONTROLLABLY ETCHING THERMALLYGROWN OXIDES. FEATURES ON THE SECOND WILL BE MADE BY ETCHING PIEZOELECTRIC THIN FILMS. USING THE PIEZOELECTRIC FILM AS PART OF A CAPACITOR, STEP-HEIGHT CAN BE VARIED AND PRO ...

    SBIR Phase I 1992 Department of Commerce
  8. THE NUMERICAL SIMULATION AND ANALYSIS OF COLD-SEASON SEVERE WEATHER EVENTS

    SBC: MESOSCALE ENVIRONMENTAL SIMULATIONS AND OPERATIONS, INC            Topic: N/A

    THE FUNDAMENTAL GOAL FOR THIS RESEARCH EFFORT IS TO DEVELOP A GREATER UNDERSTANDING OF THE DYNAMICAL PROCESSES ASSOCIATED WITH EAST COAST COLD SEASON SEVERE CONVECTIVE EVENTS AND TO NUMERICALLY SIMULATE THESE EVENTS IN ORDER TO PROVIDE HIGHER QUALITY OBJECTIVE GUIDANCE TO THE FORECASTER. THE PHASE I OBJECTIVE IS TO SHOW THE FEASIBILITY OF USING A MESO-B SCALE DYNAMICAL MODEL TO ASSIST IN THE REAL- ...

    SBIR Phase I 1992 Department of Commerce
  9. DIGESTIVE ENZYME SUPPLEMENTS TO INERT FEEDS FOR SMALL-EGG FISH LARVAE

    SBC: International Aquaculture Res            Topic: N/A

    INADEQUATE STARTER FEEDS SEVERELY HOLD BACK NEW AQUACULTURE ENTERPRISES SUCH AS PRESENT ATTEMPTS TO RAISE FISHES WHOSE LARVAE DEVELOP FROM SMALL EGGS AND HAVE VERY "DIFFICULT" FOOD REQUIREMENTS. INERT LARVAL FEEDS HAVE NOT SUCCESSFULLYELIMINATED THE STRICT DEPENDENCY ON NATURAL FORAGE DURING THE CRITICAL POST-LARVAL STAGE AFTER YOLK ABSORPTION AND BEFORE THE DEVELOPMENT OF A DIGESTIVE SYSTEM WITH ...

    SBIR Phase I 1987 Department of Commerce
  10. DESIGN OF NEXT GENERATION HYDROLOGICAL DATA MANAGEMENT SYSTEMS

    SBC: Resources Plan Assoc            Topic: N/A

    THE PROPOSED PROJECT FOCUSES ON THE PRELIMINARY DESIGN OF THE NEXT GENERATION OF HYDROLOGICAL DATA MANAGEMENT SYSTEMS. THE ISSUES TO BE ADDRESSED INCLUDE: DESIGNING FLEXIBLE, PARALLEL USER INTERFACES, DEVISING MACHINE INDEPENDENT SOFTWARE DEVELOPMENT SPECIFICATION, INCORPORATING AND IMPROVING THE CURRENT STATE-OF-THE-ART OF THE GRAPHICAL DISPLAY OF SPATIALLY AND TEMPORALLY DISTRIBUTED DATA, DEVELO ...

    SBIR Phase I 1987 Department of Commerce
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