Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Multi-Zone Flow Through Membrane and Reagents for Onsite Detection of Domoic Acid

    SBC: Mercury Science Inc.            Topic: 832

    There is a need for a simple, affordable method for measuring domoic acid in the field. This project will develop a rapid, onsite kit for domoic acid featuring a filter membrane that produces a readable color response without need for instrumentation. The filter membrane contains three or more zones with different assay characteristics in close proximity. These zones will indicate different co ...

    SBIR Phase I 2007 Department of Commerce
  2. Lab-on-a-chip for multiplexed newborn screening of lysosomal storage disorders

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Newborn screening is currently performed by collecting dried bloodspots from infants and then sending them to a lab for analysis. There is an increasing necessity to screen for a number of disease conditions for which therapies are becoming available. Lysosomal storage diseases alone number greater than 40. There is a need to minimize the blood collecte ...

    SBIR Phase I 2007 Department of Health and Human Services
  3. Interfacial Adapters for Improved Cell Delivery to Tissues

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many human diseases can theoretically be treated by injection of healthy or engineered cells into damaged tissue, where ideally they will engraft and remodel the damaged tissue into healthy tissue. However, numerous obstacles stand in the way of this regenerative technology becoming reality. Perhaps the greatest obstacle is that cells injected into many tissues ...

    SBIR Phase I 2007 Department of Health and Human Services
  4. Point of Care Attachment of Multiple Antibiotics onto Metal Implants

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infections, which arise from the establishment of biofilms on device surfaces, not only necessitate new surgeries but in themselves present a significan ...

    SBIR Phase I 2007 Department of Health and Human Services
  5. Bioactive Peptide Coatings for Synthetic Bone Grafts in Dental Applications

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): According to the National Institute of Dental and Craniofacial Research, 86% of adults over 70 years have at least moderate periodontitis and over a quarter have lost their teeth, which has serious repercussion on health and quality of life. Because of bone loss caused by this disease, bone grafting is routinely necessary prior to the placement of dental implan ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. Point of Care Adult Stem Cell Isolation

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 500,000 bone-grafting procedures are performed each year in the United States (Boden, 2002). Autologous iliac crest bone graft continues to be the gold standard because it provides the three essential elements for bone formation: osteoprogenitor cells, an osteoconductive matrix, and osteoinductive molecules. Iliac crest harvest is however associat ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. Full Range Spectral Domain Anterior Segment OCT Scanner

    SBC: BIOPTIGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Phase I Small Business Innovative Research application, Bioptigen Inc. proposes to prototype a portable, handheld cornea and anterior segment optical coherence tomography (CAS-OCT) scanner for use in clinical and applied research applications. OCT is a relatively new technology for ophthalmic imaging, which uses low-coherence interferometry to obtain cr ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. Medical Student Education on Alcohol Abuse and Dependence

    SBC: Clinical Tools, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Alcohol use disorders continue to be a growing problem in the United States. Fifty-three percent of Americans consume alcohol on a regular basis (SAMHSA, 2006). Approximately 6 percent of those users meet the criteria f or alcohol abuse or dependence (SAMHSA, 2005); 3 percent of the U.S. population. Currently, alcohol use disorders are only covered superficiall ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. Novel Intervention for Amyloid-Induced Neuroinflammation

    SBC: COGNOSCI INC            Topic: N/A

    DESCRIPTION (provided by applicant): Novel Intervention for Amyloid-Induced Neuroinflammation Extracellular deposition of the amyloid a-protein (Aa) in brain is a prominent pathological feature of Alzheimer's disease (AD) and related disorders. Fibrillar Aa deposition in the cerebral vasculature, a condition known as cerebral amyloid angiopathy (CAA), is also commonly found in AD. Additionally, se ...

    STTR Phase I 2007 Department of Health and Human Services
  10. Novel Intervention for Colitis

    SBC: COGNOSCI INC            Topic: N/A

    DESCRIPTION (provided by applicant): Novel Intervention for Colitis The scope of the current proposal is to determine whether administration of an apoE mimetic peptide, COG112, improves clinical, histological and inflammatory outcomes in clinically relevant paradigms of colitis. Specifically, we will employ the acute Citrobacter rodentium (C. rodentium) model, an acute Dextran Sulfate Sodium (DSS) ...

    STTR Phase I 2007 Department of Health and Human Services
US Flag An Official Website of the United States Government