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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Microcapillary Quartz Sensors for Screening Injectability of High Concentration Protein Formulations

    SBC: QATCH TECHNOLOGIES LLC            Topic: None

    The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

    SBIR Phase I 2019 Department of CommerceNational Institute of Standards and Technology
  2. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: ZYMERON CORP            Topic: CBD181004

    Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Multi-Zone Flow Through Membrane and Reagents for Onsite Detection of Domoic Acid

    SBC: Mercury Science Inc.            Topic: 832

    There is a need for a simple, affordable method for measuring domoic acid in the field. This project will develop a rapid, onsite kit for domoic acid featuring a filter membrane that produces a readable color response without need for instrumentation. The filter membrane contains three or more zones with different assay characteristics in close proximity. These zones will indicate different co ...

    SBIR Phase I 2007 Department of Commerce
  4. Microbial Community Microarrays to Assess Chemical and Biological Characteristics of Water Quality

    SBC: SOUTHEAST TECHINVENTURES INC            Topic: N/A

    This Phase I SBIR project intends to demonstrate the feasibility of a freshwater microbial community microarray called the WaterChipTM, for detecting the presence of an important model for mercury chemical pollutant in freshwater. By demonstrating its utility for detecting evidence of this pollutant, the basis for expanding the WaterChips capability to other environmental toxins and pollutants wi ...

    SBIR Phase I 2007 Environmental Protection Agency
  5. Microbial Community Microarrays to Assess Chemical and Biological Characteristics of Water Quality

    SBC: SOUTHEAST TECHINVENTURES INC            Topic: 06NCERA1

    This Phase I SBIR project intends to demonstrate the feasibility of a freshwater microbial community microarray, called the WaterChip™, for detecting the presence of an important model for mercury chemical pollutant in freshwater. By demonstrating its utility for detecting evidence of this pollutant, the basis for expanding the WaterChip’s capability to other environmental toxins and pollutan ...

    SBIR Phase I 2007 Environmental Protection Agency
  6. Construction of a Force Probe for Characterization of Microscale Features

    SBC: INSITUTEC, INC.            Topic: N/A

    The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...

    SBIR Phase I 2005 Department of CommerceNational Institute of Standards and Technology
  7. Handheld Photoacoustic Chemical Agent and Toxic Industrial Material Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. NANOMETER-SIZE STEP HEIGHT TEST STRUCTURES

    SBC: Advanced Technologies/Laboratories Intl            Topic: N/A

    MCNC PROPOSES A FEASIBILITY STUDY AND EVALUATION OF THREE PROMISING APPROACHES TO THE FABRICATION OF SURFACE TEST STRUCTURES ON SILICON. SURFACE FEATURES ON THE FIRST STRUCTURE WILL BE PRODUCED BY CONTROLLABLY ETCHING THERMALLYGROWN OXIDES. FEATURES ON THE SECOND WILL BE MADE BY ETCHING PIEZOELECTRIC THIN FILMS. USING THE PIEZOELECTRIC FILM AS PART OF A CAPACITOR, STEP-HEIGHT CAN BE VARIED AND PRO ...

    SBIR Phase I 1992 Department of Commerce
  9. DIGESTIVE ENZYME SUPPLEMENTS TO INERT FEEDS FOR SMALL-EGG FISH LARVAE

    SBC: International Aquaculture Res            Topic: N/A

    INADEQUATE STARTER FEEDS SEVERELY HOLD BACK NEW AQUACULTURE ENTERPRISES SUCH AS PRESENT ATTEMPTS TO RAISE FISHES WHOSE LARVAE DEVELOP FROM SMALL EGGS AND HAVE VERY "DIFFICULT" FOOD REQUIREMENTS. INERT LARVAL FEEDS HAVE NOT SUCCESSFULLYELIMINATED THE STRICT DEPENDENCY ON NATURAL FORAGE DURING THE CRITICAL POST-LARVAL STAGE AFTER YOLK ABSORPTION AND BEFORE THE DEVELOPMENT OF A DIGESTIVE SYSTEM WITH ...

    SBIR Phase I 1987 Department of Commerce
  10. "MITIGATION OF ACID RAIN AND OXIDANT IMPACTS ON CROPS AND FORESTS UTILIZING MARINE EXTRACTS"

    SBC: Maricultura Inc            Topic: N/A

    RECENT ASSESSMENTS ESTIMATE U.S. CROP LOSSES FROM ELEVATED OZONE LEVEL AND OTHER OXIDANTS (SULFUR DIOXIDE, NITROGEN DIOXIDE) TO BE AS MUCH AS $5 BILLION ANNUALLY. ADDITIONALLY,SEVERE FOREST DAMAGE MAY RESULT FROMPOLLUTION-RELATED OXI- DANTS PARTICULARLY IN EUROPE WHERE THERE HAS BEEN A DRAMATICDECLINE IN FOREST ECOSYSTEMS OVER THE PAST SIX YEARS. THIS RESEARCH IS DIRECTED AT THE MITIGATION OF SUCH ...

    SBIR Phase I 1987 Environmental Protection Agency
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