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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Insensitive Munitions Modeling and Simulation

    SBC: 3D RESEARCH CORP.            Topic: A05201

    3D Research Corporation and Aerojet, Incorporated, propose a novel approach to munitions modeling to assure the munitions meets Insensitive Munitions (IM) requirements of DoDD 5000.2-R and MIL-STD-2105C. IM validation of munitions requires extensive testing, and it is necessary to develop analytical approaches which accelerate the design process for IM compliance. The proposed approach evaluates ...

    SBIR Phase I 2005 Department of DefenseArmy
  2. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Nanodroplet PCR Lab-Chip for Clinical Pathogen Detection

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Rapid and accurate detection and identification of pathogens is crucial for the effective management and treatment of infectious disease. While molecular diagnostic techniques including PCR are a promising approach for rapid and sensitive detection of pathogens, they suffer from a number of technical drawbacks which have slowed their acceptance in the clinic. ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Helicopter Remote Manipulation of External Slingloads (HERMES)

    SBC: Advanced Optical Systems, Inc            Topic: A05057

    Helicopter operations in low visibility conditions and sling load operations continue to add risk to aviation operations. If slingloads could be picked up without use of a ground crew, lives could be saved. In addition, a sensor that could detect obstacles as well as the load would help in low-visibility conditions. We propose to develop such a system. It will include the mechanical structures nec ...

    SBIR Phase I 2005 Department of DefenseArmy
  5. Discovery of Peptide-based Bone Morphogenic Protein Mimetics

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this proposal, we present a novel approach for the identification and immobilization of a BMP mimetic. We plan to use phage display technology to identify peptides that mimic BMP-like signaling of the BMP receptors. These peptides will be linked to a previously identified high-affinity, collagen-binding peptide. The resulting hybrid molecule will allow contr ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Improved Orthopedic Implant Surface Coatings

    SBC: AFFINERGY, LLC            Topic: N/A

    Endosseous metallic implants are common alloplastic devices used in medicine and dentistry. The orthopedic and dental marketplace continues to grow and indications for implants are expanding. There is a perceived need to improve both the successful healing (osseointegration) and the long term outcome of implants by control of interfacial reactivity during healing and remodeling. The growth of know ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Molecular Heparan Sulfate Delivery in Wound Regeneration

    SBC: International Medicine and Biomedical Research            Topic: N/A

    DESCRIPTION (provided by applicant): Tissue engineering, grafting procedures, regeneration, and tissue remodeling are developing therapies with great potential medical value. None of these therapeutic modalities are yet fully effective or predictable. Glycosaminoglycan-decorated proteoglycans such as perlecan, once thought to primarily serve as structural components of extracellular matrix, are no ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Electrochemical RT activity assay for measuring HIV load

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Phase I SBIR project Alderon Biosciences Inc. (ABI) proposes to demonstrate the feasibility of using electrochemical reverse transcriptase (eRT) assays for determinations of HIV viral load in clinical samples. Success will set the stage for Phase II development, FDA approval, and production of commercial kits using this advanced technology. The long-r ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Electrochemical Quantification of HCV RNA

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The National Institutes of Allergy and Infectious Disease have called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases. To meet this need, Alderon Biosciences Inc. (ABI) proposes to develop innovative, low-cost tests with sensitivity adequate for determining HCV viral load. Reliable and affordable HCV viral load t ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
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