Award Data

The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

The overall goals of our effort are to reduce the cost and lead times of test articles while maintaining their fidelity. Corvid Technologies will partner with North Carolina State University to examine why metal alloys produced by AM processes differ in high strain-rate response compared to traditional foundry (TM) alloys at their CAMAL facility. We will identify the differences in response by exa ...

Vigilant Cyber Systems, Inc. (VCS) proposes to design and develop the Manipulation Analysis and Visualization (MAV) Tool to enable users to analyze extremely large and diverse multi-dimensional datasets and gain insight into the data and the phenomena that produced the data. MAV will revolutionize analysis of modeling and simulation and test data by significantly enhancing user cognition and enabl ...

Vadum has demonstrated the Optimal Advanced Hypervelocity Projectile (HVP) Trajectory System (OATHS) which increases the performance of the HVP by optimizing HVP trajectory to its target. OATHS was prototyped and tested using an in-house MATLAB-based combat system development environment. The results of Phase I testing show that OATHS can feasibly increase HVP probability of kill or reduce the tot ...

Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

The development of a generalized moving body capability for Computational Fluid Dynamics (CFD) flow simulations of highly transient flowfields is critical to system analyses of Divert and Attitude Control Systems (DACS) for Kinetic Warheads (KWs). Testing capabilities are limited in the DACS operating regime; therefore, computational tools are essential for such analyses. The flow in the DACS its ...

The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...

Ultra-high performance multi-function RF electronics are required by the United States Department of Defense to enable next generation radar and sensor networks in response to an increasingly diverse array of threats to our military and our homeland. An elegant potential solution is that of gallium nitride (GaN) RF electronics, which has shown great promise on currently available yet foreign subs ...

Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...