Award Data

Our nation faces increasing challenges in meeting the special needs of elderly and disabled individuals. Non-ambulatory persons with visual impairment, diminished upper-body mobility, spasticity/tremors, memory/attention deficits and other problems may require extraordinary care measures because they can operate neither powered nor manual wheelchairs successfully. Current state-of-the-art motorize ...

This Small Business Innovation Research Phase I project will integrate materials processing and will develop a new lightweight and resilient three-dimensional woven fiber reinforced cellular matrix composite (3DCMC) material. Lightweight materials will allow fuel efficient and more environmentally friendly vehicles. The 3DCMC have the potential to significantly surpass the strength, stiffness, d ...

Alderon Biosciences proposes to develop a new electrochemical method for detection of specific nucleic acid sequences without enzymatic, fluorescent or radioactive labels and to show the feasibility of applying this method in an electrochemical plate (E-Plate) format to studies of gene expression in cancer. The E-Plate, an electrical analog of a traditional microplate and reader, will be developed ...

DESCRIPTION (provided by applicant): The goal of this project is to improve the health of women and infants by enabling crucial research in areas such as SIDS, insufficient or excessive maternal weight gain, short interpregnancy intervals, and birth defects. Advances in understanding the causes and prevention of these and other problems require studies that include more than one pregnancy/birth fo ...

DESCRIPTION (provided by applicant): The goal of this project is to improve the health of women and infants by enabling crucial research in areas such as SIDS, insufficient or excessive maternal weight gain, short interpregnancy intervals, and birth defects. Advances in understanding the causes and prevention of these and other problems require studies that include more than one pregnancy/birth fo ...

his Small Business Technology Transfer Phase I project is to design and develop appropriate mathematical models and algorithms for optimizing the crosscut operation in a wood processing (lumber processing) rough mill. The goal is to incorporate these algorithms into an integrated software system for automatic control of the process. The software system consists of a main engine that contains the m ...

"The DNA microarray is a powerful new technology that can be applied to the detection of biological warfare agents. For the detection of multiple agents, tremendous challenges lie ahead for the DNA microarray technology regarding on sensitivity,selectivity, reliability and consistence. The central theme of this proposal is to apply and optimize a newly developed DNA probe: Molecular beacons (MB) ...

DESCRIPTION (provided by applicant): BioMachines describes a specific innovation in multichannel, small volume fluid handling, the Microfluid Processor Chip (MPC). The MPC is an original fluid handling device based on arrayable, disposable chips, initially fabricated from silicon that will enable highly accurate, low cost ...

DESCRIPTION (provided by applicant): Development of a new method for prophylaxis and treatment of urinary stone disease is proposed. Since a majority of urinary stones are made of calcium oxalate, the level of urinary oxalate is one of the major risk factors of stone formation. Unfortunately, there is no effective pharmacological treatment of stone disease that targets urinary oxalate concentratio ...

DESCRIPTION (provided by applicant): A major contamination issue at over 8,000 sites in the United States are PAHs. This contamination results from almost all combustion processes, creosote treatment of wood, former town gas sites, and many others. Many of these chemicals are both toxic and carcinogenic. It has been observed that these highly hydrophobic chemicals bind tightly to soil by a numb ...