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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Rapid, Quantitative Biological Indicator System with Bacillus thuringiensis Al Hakam Spores(1001-677)

    SBC: TRITON SYSTEMS, INC.            Topic: CBD11101

    Biological agents pose high threats, because they are invisible and odorless and a relatively small amount can infect a large population when released in a densely populated area. For the same reasons, assuring safety after cleaning decontaminated sites can be challenging. Currently available technologies require considerable labor, and results typically cannot be obtained before 24 V 48 hours up ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  2. Ruggedized FTIR Spectrometer Based on Calomel Prisms

    SBC: AGILTRON, INC.            Topic: CBD11104

    Leveraging on Agiltron industry leading development of optical systems and the PI experience with FTIR spectrometer design, we propose to develop a new class of compact monolithic Fourier-transform spectrometers for the long-wave (7.5-13 m) infrared optical range. The proposed solution is based on creating a spatial interferogram with a pair of a calomel Wollaston prisms and digitizing it with an ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  3. Microfluidic High-throughput Platform for Determining Kinetic Constants of Enzyme Variants

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10107

    Current high-throughput platforms rely on labeled substrates that produce detectable spectroscopic signals upon reaction for monitoring enzyme catalytic activity. Add to that the high price tag for these instruments, ranging from several hundred thousand to millions of dollars, and there is a clear need for alternate solutions for a label-free, low-cost, high-throughput enzyme screening platform. ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  4. A Novel Microfludic Device for Drug Toxicity Studies

    SBC: CFD RESEARCH CORPORATION            Topic: CBD10103

    Current drug discovery and development efforts are severely limited by expensive animal trials and oversimplified in vitro models. Results obtained from in vitro models are not predictive of in vivo toxicity owing to significant difference from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device that reproduces the physiological ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Low noise longwave infrared (8-12µm) focal plane array with high sensitivity for passive hyperspectral standoff detection

    SBC: APPLIED NANOFEMTO TECHNOLOGIES LLC            Topic: CBD10105

    Longwave infrared (LWIR, 8-12µm) focal plane arrays (FPAs) play an important role in hyperspectral chemical and biological (CB) sensing and spectral imaging. Existing thermal detectors are unable to meet the high sensitivity and fast response requirements of many hyperspectral chemical and biological sensing applications. FPAs based on photon excited electron generation process can fulfill the sp ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. MEMS Lamellar Based Interferometer for the Detection of Toxic Chemicals

    SBC: AGILTRON, INC.            Topic: CBD10104

    Leveraging on Agiltron industry leading development of optical MEMS devices and the PI experience with FTIR spectrometer design, we propose to develop a new class of high performance compact and rugged FTIR spectrometers for the LWIR optical range. The design is based on the MEMS lamellar mirror technique. Although this approach is not new, it has not yet been efficiently applied to LWIR, and per ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  7. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. Monitoring Food and Water for Pathogens

    SBC: BIOSCALE, INC.            Topic: CBD03201

    Having achieved or exceeded all goals and objectives of the Phase I research program, BioScale has thus demonstrated feasibility of a multiplexed, immuno-electromechanical pathogen detection method. In Phase II, BioScale proposes to advance this research by assembling a complete assay system that integrates discrete, commercial off the shelf (COTS) sample preparation subcomponents with the propri ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  9. Toxin-Neutralizing Barrier Skin Cream for CWA Protection

    SBC: Cape Cod Research            Topic: CBD05118

    The threat of chemical and biological (CB) warfare agent exposure requires a variety of measures to protect military personnel. CB agent entry through the skin can potentially be reduced through the application of chemical barrier creams. Low surface energy fluoropolymers have been shown to resist penetration of both polar and nonpolar chemicals. A new protective skin cream is proposed that uti ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  10. Handheld Photoacoustic Chemical Agent and Toxic Industrial Material Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
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