Award Data

The goal of this proposal is find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic agents available to treat filovirus infections and the de ...

The purpose of this STTR phase I proposal is to demonstrate the feasibility of producing the survivable multi-functional engineered material systems for spacecraft surfaces at an affordable cost using the proposed novel material designs and processes. The objectives of these efforts are not only to demonstrate the technical feasibility, but also to illustrate that at least 50% cost savings for DOD ...

The development of a generalized moving body capability for Computational Fluid Dynamics (CFD) flow simulations of highly transient flowfields is critical to system analyses of Divert and Attitude Control Systems (DACS) for Kinetic Warheads (KWs). Testing capabilities are limited in the DACS operating regime; therefore, computational tools are essential for such analyses. The flow in the DACS its ...

Most seeker systems usually operate at long distances. The return laser signal from the target is not only attenuated by absorption, reflection and scattering by air-borne gas, dust and liquid particles, but also by the emissivity and reflectivity variations of the target surface. High bandwidth detectors with internal gain are required. Avalanche photodetectors (APDs) are best suited for this pur ...

This proposal deals with new techniques for the guidance and control of Boost Phase of the missile defense. A new concept integrating the synergy between guidnace and coontrol is offered as an Integrated Guidance and Control approach; furthermore, a new nonlinear controller-filter called the theta-D technique is offered as the tool to solve the boost phase guidance and control problem for accurate ...

Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

The overall objective of this proposal is to demonstrated that imidazenil is a more potent and safer protective agent than diazepam against chemical warfare nerve agent (CWNA)-induced seizure/status epilepticus, neuropathology, and neurobehavioral deficits. Thus we will compare the dose-dependent efficacy of imidazenil or diazepam administered alone and in combination with levetiracetam in protect ...

In this STTR Phase I project Vega Wave Systems, Inc. will develop and demonstrate III-V native-oxide defined InGaP-GaAs heterojunction bipolar transistors (HBTs) for integrated X-band radar transmit/receive modules. The Phase I objective is to leverage prior demonstrations of III-V native oxide defined HBTs in order to achieve high device performance for both power amplifier (PA) and low-noise amp ...

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