Award Data

To address the U.S. CBD need for novel autoinjector technology that provides the warfighter with a compact, field-ready, cost-effective platform for long-term storage of any given CBT antidote that does not present a significant logistical burden, Physical Optics Corporation (POC) proposes to develop a Microfluidic Pneumatic Autoinjector (MPA) platform. The MPA will provide an innovative universal ...

Oraganophosphorus poisons are potent nerve agents that function by inhibiting the action of acetylcholinestrase in nerve cells. Of these, G-class nerve agents including: Taubin, Soman and Saurin, and, V class agents such as VX represent a significant threat to US military personnel. Human plasma enzyme, Butyrylcholinesterase detoxifies organophosphates by making a covalent bond with them at stoich ...

A novel high-sensitivity biodosimeter technology is proposed that can perform rapid, non-invasive measurement radiation biomarkers in solid human tissues such as fingernails and teeth.

We propose a next-generation reader system for Rapid Diagnostic Tests using lateral flow immunoassay cartridges. The system includes a rugged and lightweight reader that is built on a cellphone platform, a centralized data server, and bio-surveillance application software. The server communicates with readers securely over Internet, cellular and other networks. Reader design aims to provide the ...

A new and promising algorithm is proposed based on hyperspectral unmixing by a sequential processor that will be further developed for data fusion to both enhance sensor sensitivity and eliminate the need for separate background interrogation, thereby allowing for fast real time detection. Sensor sensitivity will be improved by a combination of passive FTIR spectroscopy, and active thermal imagin ...

We will continue developing a plasmonic metamaterial with strong absorption within a narrow band that is dynamically tunable over the 8-10 micron range. A metamaterial consisting of one or more bi-layers of thin metal and dielectric films will trap, concentrate and absorb a narrow frequency band while strongly reflecting out-of-band light. Tuning the frequency of the absorption band may be achiev ...

"The DNA microarray is a powerful new technology that can be applied to the detection of biological warfare agents. For the detection of multiple agents, tremendous challenges lie ahead for the DNA microarray technology regarding on sensitivity,selectivity, reliability and consistence. The central theme of this proposal is to apply and optimize a newly developed DNA probe: Molecular beacons (MB) ...

"Wearable, passive detectors for toxic industrial chemicals (TICs) and chemical warfare agents (CWAs) will greatly improve the safety of military personnel operating in chemically-threatened environments. Cyrano Sciences, Inc. (CSI) uses polymer-compositesensor technology to construct sensor arrays, that are uniquely positioned to address applications, such as detector badges for TICs and CWAs, t ...

"Widespread concern about the prospects of chemical assaults has raised demand for a miniature low-power high resolution wideband spectroscopic sensor for real-time characterization and identification of chemical agent clouds and vapors. Current devicesonly cover narrow bandwidths, and hence require multiple modules to cover the UV, visible, and near IR spectral bands, increasing system weight, s ...

We propose a new type of military smoke that is based on the optical properties of selectively designed, yet low cost, fabricated nanoscale components. These smokes will have a strong extinction in the visible and infrared regions of the spectra, but canalso selectively block or let pass specific wavelengths of light. Such a smoke can be designed to have a field-selectable transmissive window th ...