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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Treatment for alcoholic liver disease

    SBC: Angion Biomedica Corp.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Liver fibrosis is a form of scar formation that is found in almost all patients with chronic injury to the liver. Over time it frequently progresses to cirrhosis, an end-stage lethal disease which is the seventh leadingcause of death in the United States and afflicts hundreds of millions of people worldwide. Alcohol intake remains the most important cause of li ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Antagonism of Alpha2A-Adrenoceptor: A Novel Anti-Sepsis Therapy

    SBC: THERASOURCE, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): This SBIR Phase II proposal is a plan to further develop a novel therapeutic approach that will save the lives of patients with sepsis. Despite the increased understanding of the complex pathophysiology of sepsis, severe sepsis still results in significant morbidity and mortality. As such, there is an urgent unmet medical need for an effective novel therapy for ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid DPP test for tuberculosis

    SBC: CHEMBIO DIAGNOSTIC SYSTEMS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis with an estimated two billion people currently infected worldwide and over nine million new cases detected annually worldwide. This is the largest killer of patients with HIV/AIDS. Current methods of diagnosis are complex, time-consuming, unreliable or unaffordable for most countr ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Delivery of Nanoencapsulated TGFbeta and ATRA for the Treatment of IBD

    SBC: THERAPYX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Phase I studies established proof-of-principle for the efficacy of oral sustained-release TGF?1 (TPX-6001) and ATRA (TPX-7001) nanoparticles in the treatment of IBD in a murine adoptive T-cell transfer model. Specifically, a two-week regimen of oral TPX-6001 and TPX-7001 achieved a 50-90 % reduction in the severity of multiple disease indicators in mice with ad ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Organismal Radioprotection Through Pharmacological Quiescence

    SBC: G1 THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Syndrome (ARS), including a lethal myelosuppression due to the sensitivity of proliferating hematopoietic stem/progenitor cells (HSPCs) to ionizing radiation (IR). No effective therapy exists to mitigate the hematologictoxicities of TBI. Herein G-Zero Therapeutics seeks to further the proprietary development of small molecule inhibitors of cyclin-dependent kina ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Point of Care Adult Stem Cell Isolation

    SBC: AFFINERGY, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Approximately 500,000 bone-grafting procedures are performed each year in the United States.5 Autologous iliac crest bone graft continues to be the gold standard, because it provides essential elements for bone formation: progenitor cells, an osteoconductive matrix, and osteoinductive molecules. However, iliac crest harvest is associated with a significant numb ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Validation and commercialization of a/LCI for detection of esophageal neoplasia

    SBC: Oncoscope, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): The objective of this research is to commercialize a device (the Oncoscope Panocyte system) used to guide biopsy selection in patients with Barrett's esophagus (BE) during standard endoscopy surveillance for early- stage esophageal cancer. Barrett's esophagus most often develops in patients with chronic acid reflux and is the strongest risk factor fo ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Infrared and X-ray Nanogold Therapy of Head and Neck Cancers

    SBC: NANOPROBES INC            Topic: NCI

    DESCRIPTION (provided by applicant): This proposal is based on a recent discovery that tumors can bioconvert non-absorbing small metal nanoparticles into intense infrared (IR) absorbers. In preliminary tests, non-IR absorbing 15 nm gold nanoparticles wereimmunotargeted to human tumors in mice which then became highly IR absorbing. The amplification factor in IR absorption can be a factor of 20 or ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  9. CT Image Estimation for Calculation of Delivered Dose

    SBC: MORPHORMICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The prostate is a mobile organ that demonstrates momentary and daily changes in position and shape that critically affect accurate delivery of radiation therapy. For this reason, in modern technically demanding radiation therapy for prostate cancer, it is standard practice to localize the prostate on most days treatment as an aid to achieve the goal of deliveri ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  10. A Nanotechnology Enabled Diagnostic Platform for Early Stage Cancer Detection

    SBC: INANOVATE INC            Topic: NCI

    DESCRIPTION (provided by applicant): The objective of this proposal is the development, evaluation and validation of an accurate, low cost diagnostic test that can discriminate prostate cancer from benign prostatic hyperplasia to a Specificity of 85% at aSensitivity of 85%. Prostate cancer is the most common cancer in men, with a probability of 1 in 6. Approximately 29% of all cancer cases in ma ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
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