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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Lab on a chip point of care assay for the rapid serodiagnosis of Lyme disease

    SBC: BIOPEPTIDES CORP            Topic: NIAID

    DESCRIPTION (provided by applicant): Caused by Borrelia burgdorferi, Lyme Disease (LD) can affect the skin, heart, joints or nervous system leading to an array of symptoms that overlap with those of other illnesses. LD is the most common vector-borne infectious disease in the United States and remains a significant public health concern. Early diagnosis and treatment is key to improving disease ou ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Nitric Oxide-Releasing Intranasal Gel To Decolonize Biofilm-embedded S. Aureus

    SBC: Novan, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Staphylococcus aureus is the second leading cause of hospital-acquired bloodstream infections. In 2003, nearly 300,000 patients in US hospitals acquired an S. aureus infection, which accounted for nearly three million days of hospitalization, 9.5 billion in excess costs, and at least 12,000 inpatient deaths. Additionally, approximately 50% of the US population ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Safe and Efficacious Oral MIF Inhibitors for Rheumatoid Arthritis Treatment

    SBC: INNOVIMMUNE BIOTHERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): There are high unmet medical needs in the limited biologic therapeutics for 1.0% of adults with rheumatoid arthritis [RA] associated with staggering 39.2 billion annual US health care and societal costs. These are dueto inadequate efficacy; patient's inconvenience, prohibitive costs, poor adherence and treatment discontinuations; manufacturing risks and s ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Preventing Burn Wound Infection Using a Novel Free Radical Sterilization System

    SBC: GOLKOWSKI CZESLAW            Topic: NIAID

    DESCRIPTION (provided by applicant): Approximately two million burn injury cases require medical attention on a yearly basis in the United States alone, with 20,000 of these cases requiring admission to specialized burn centers. One of the foremost causesof morbidity and mortality in the burn patient is infection. Indeed, for those patients with burn size greater than 40% of total body surface are ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Human Ghrelin As An Effective Mitigator of Acute Radiation Injury

    SBC: THERASOURCE, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): This SBIR Phase I proposal is intended to demonstrate the feasibility of developing a novel and effective therapeutic approach that can save lives of people with radiation injury. Acute radiation injury may occur in various incidents as well as the terrorist radiation exposure scenario. Acute radiation syndrome develops after whole-body or a partial-body irradi ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a human skeletal muscle cell-based high throughput screen for musc

    SBC: Zen-Bio, Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Skeletal muscle wasting is a serious condition prevalent in the aging population (sarcopenia) and in a variety of specific diseases. This condition results in loss of muscle function through impaired muscle regeneration, resulting in an increase in falls and injuries, a loss of independence, and a reduced quality of life. These changes produce a large health ca ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Web-Based Dissemination of Evidence-Based Prevention to U.S. Military

    SBC: National Health Promotion Associates, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): This Phase I SBIR grant application requests six months of funding to develop and feasibility test an innovative Web-based distribution channel for increasing the dissemination, adoption, implementation, and sustainability (DAIS) of evidence-based substance use prevention programs to United States military personnel. Substance use and abuse, particularly heavy ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Online Training on Opioid Overdose Prevention, Recognition, and Response

    SBC: SOCIAL SCIENCES INNOVATIONS CORPORATION            Topic: NIDA

    DESCRIPTION (provided by applicant): We propose to translate a successful, efficacious, CASAC-approved overdose prevention, recognition and response training curriculum (S.K.O.O.P-Skills and Knowledge on Overdose Prevention) utilized in NY State into an online Computer-Assisted Instructional (CAI) format to significantly impact the dissemination of this life- saving, community-based curriculum, na ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. An Interactive Text Messaging Intervention to Improve Drug Court Outcomes

    SBC: SOCIAL SCIENCES INNOVATIONS CORPORATION            Topic: NIDA

    DESCRIPTION (provided by applicant): Drug Courts reflect the cutting edge of new, innovative treatments for substance abuse. A text messaging system integrated as part of the Drug Court's treatment program holds the promise of improving treatment outcomesand has positive market potential. Shorter, less-costly, more effective treatment may be possible with the addition of a telephone texting s ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Multifunctional, Nanoparticle-Based, Therapies for the Treatment of Periodontal D

    SBC: TRANSPARENT MATERIALS, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): The objective of this Phase I SBIR proposal is to provide improved therapies for the treatment of periodontal disease. Periodontal Disease is a chronic infectious disease of the oral cavity that effects about 35 % of the adult population in the United States, or slightly more than 40 million people.1-12 In severe cases, periodontal disease can lead to a failure ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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