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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Concurrent identification of Natural Antibiotics-Producing Gene Clusters and Culture Conditions

    SBC: Carrera Bioscience Inc.            Topic: CBD152004

    Modern metagenomics studies on diverse microbiomes revealed immense repertoires of potential natural products/antibiotics to be tapped into.However, identifying such secondary metabolites (SMs) directly from a complex microbiome remains rarely successful due to two major technicalchallenges: i) difficulty in dissecting complex microbiome samples and massive metagenomics data, and ii) difficulty in ...

    SBIR Phase I 2015 Department of DefenseOffice for Chemical and Biological Defense
  2. Innovative concept for detection and identification of biological toxins

    SBC: PHOEBUS OPTOELECTRONICS LLC            Topic: CBD14101

    We aim to create a low-cost, high-sensitivity hand-held plasmonic biosensor capable of sensing biotoxins. We will do this by using newly developed biodesign technology to create a new class of proteins which have an orders-of-magnitude increase in SPR signal-to-noise. These will be incorporated into a novel SPR device in which the transmission of light is affected by the binding of a particular t ...

    SBIR Phase I 2014 Department of DefenseOffice for Chemical and Biological Defense
  3. Narrowband Perfect Absorber using Metamaterials

    SBC: PHOEBUS OPTOELECTRONICS LLC            Topic: CBD11102

    We propose a metamaterial-enhanced microbolometer with strong absorption over a narrow band that is dynamically tunable over the 8-10 micron band. A single-layer photonic metamaterial consisting of a thin metal film perforated with a 2-D array of dielectric apertures will be deposited on an amorphous-Silicon layer acting as an absorber and bolometer. The metamaterial, in conjunction with planar di ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  4. Multiplex Microsphere Assay for Botulinum Neutralizing Antibodies

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD11109

    Currently, the accepted standard experimental model for measuring protective efficacy against botulism is the Mouse Lethality Neutralization (MLN) assay. Botulism poisoning is a life threatening condition that is not only a public health concern, but could also be a potential biological weapon. With seven serotypes of botulinum neurotoxins, there is need for an alternative to the MLN assay due t ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. Handheld FT-IR/Photoacoustic Chemical Agent Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes development of the MP-100 handheld FT-infrared photoacoustic chemical agent detector, following a highly successful Phase I effort. Chemical attacks and accidents can be mitigated partially by cost-effective sensors. High priority programs will benefit from a sensor compliant to Joint Warning & Reporting Network (JWARN) standards. The device is ideally suited to ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
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