Award Data

Our goal in this SBIR project is to develop a lightweight, low-power, inexpensive hyperspectral spectro-polarimetric imaging sensor for wide area standoff detection of chemical agents. The imaging system will employ an acousto-optic tunable filter (AOTF) that operates in the LWIR wavelength range. The sensor will have polarimetric imaging capabilities which, adds a valuable signature feature to im ...

This effort will expand the universe of direct energy enhancers across a wider spectrum of RF parameters to produce optimal decontamination at even lower cost. During the course of the Phase II investigation proposed here, initial work will be carried out on the determination of the fundamental mechanism of decontamination of biological materials with an eye toward expanding applicability to chemi ...

The synthetic opioids fentanyl and carfentanil pose an imminent national security threat, given the ease with which they can be obtained, their low lethal doses, and their potential for weaponized use. The purpose of this agreement is to adapt SensoDx’s high-performance miniaturized diagnostics platform based on a programmable bio-nano-chip, with embedded artificial intelligence, to enable U.S. ...

Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

The preponderance of biosensors under development today rely on labeling reagents such as fluorescent, radioisotopic or enzymatic tags. As a result, the added complexity of these reagents and their incorporation into the detection system has resulted in designs that are difficult to implement or that require significant sample preparation steps before introduction into the detection instrument. ...

Current geopolitical strategies require effective warfare countermeasures to protect U.S. forces against biological and chemical threats. Today's molecular biology and immunological detection technologies cannot be used to produce automated biodetectors useable in the battlefield. New, improved detection technologies are needed to minimize the impact of chemical and biological weapons on Army per ...