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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: ZYMERON CORP            Topic: CBD181004

    Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. A Next Generation, High-Precision, Field Drug Detection System

    SBC: SensoDX II, LLC            Topic: A16AT008

    The synthetic opioids fentanyl and carfentanil pose an imminent national security threat, given the ease with which they can be obtained, their low lethal doses, and their potential for weaponized use. The purpose of this agreement is to adapt SensoDx’s high-performance miniaturized diagnostics platform based on a programmable bio-nano-chip, with embedded artificial intelligence, to enable U.S. ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Dermal Medical Countermeasures for Chemical Weapons Exposure

    SBC: ZYMERON CORP            Topic: CBD161003

    The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...

    SBIR Phase I 2017 Department of DefenseOffice for Chemical and Biological Defense
  4. Signal Processing for Layered Sensing

    SBC: VADUM INC            Topic: CBD152006

    Vadum will develop Chemical, Heterogeneous sensor fusion Incident awareness Module (CHIME)asoftware module that will ingest data from a large number of asynchronous, heterogeneous and multi-tiered sensors to automate the process of estimating the source attributes of a chemical or biological release. CHIME generates estimates from a continuous stream of raw sensor data with successive estimates al ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  5. Narrowband Perfect Absorber using Metamaterials

    SBC: PHOEBUS OPTOELECTRONICS LLC            Topic: CBD11102

    We propose a metamaterial-enhanced microbolometer with strong absorption over a narrow band that is dynamically tunable over the 8-10 micron band. A single-layer photonic metamaterial consisting of a thin metal film perforated with a 2-D array of dielectric apertures will be deposited on an amorphous-Silicon layer acting as an absorber and bolometer. The metamaterial, in conjunction with planar di ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. Multiplex Microsphere Assay for Botulinum Neutralizing Antibodies

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD11109

    Currently, the accepted standard experimental model for measuring protective efficacy against botulism is the Mouse Lethality Neutralization (MLN) assay. Botulism poisoning is a life threatening condition that is not only a public health concern, but could also be a potential biological weapon. With seven serotypes of botulinum neurotoxins, there is need for an alternative to the MLN assay due t ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  7. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. IMPROVED STEADY-STATE INITIALIZATION ALGORITHMS FOR COMPUTER CODES

    SBC: Compu Simulation & Anal I            Topic: N/A

    N/A

    SBIR Phase I 1992 Nuclear Regulatory Commission
  9. RISK-BASED ANALYSIS OF TECHNICAL SPECIFICATIONS

    SBC: Applied Biomathematics Inc            Topic: N/A

    N/A

    SBIR Phase I 1987 Nuclear Regulatory Commission
  10. DEVELOP AN INHALATION SCREENING DOSE MONITOR FOR WORKERS AT NUCLEAR POWER PLANTS

    SBC: Mikayola International            Topic: N/A

    AN "INHALATION SCREENING DOSE COLLAR-STANCHION MONITOR" WITHEMBEDDED MINIATURE THIN-WALL GEIGER-MUELLER RADIATION DETECTORS EVALUATES THE THYROID GLAND FOR NANOCURIE ACTIVITYINVENTORY. THE PRIMARY TECHNICAL OBJECTIVE IS TO ESTABLISH THAT THE "COLLAR-STANCHION MONITOR" WILL BE CAPABLE OF DETECTING WITHIN 15 SECONDS AND WITH 2 SIGMA CONFIDENCE AN ACTIVITY INVENTORY OF 0.7 NANOCURIES OF I-131 DOSE EQ ...

    SBIR Phase I 1987 Nuclear Regulatory Commission
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