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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: Zymeron Corporation            Topic: CBD181004

    Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  2. A Next Generation, High-Precision, Field Drug Detection System

    SBC: SensoDX II, LLC            Topic: A16AT008

    The synthetic opioids fentanyl and carfentanil pose an imminent national security threat, given the ease with which they can be obtained, their low lethal doses, and their potential for weaponized use. The purpose of this agreement is to adapt SensoDx’s high-performance miniaturized diagnostics platform based on a programmable bio-nano-chip, with embedded artificial intelligence, to enable U.S. ...

    SBIR Phase II 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Narrowband Perfect Absorber using Metamaterials

    SBC: Phoebus Optoelectronics LLC            Topic: CBD11102

    We propose a metamaterial-enhanced microbolometer with strong absorption over a narrow band that is dynamically tunable over the 8-10 micron band. A single-layer photonic metamaterial consisting of a thin metal film perforated with a 2-D array of dielectric apertures will be deposited on an amorphous-Silicon layer acting as an absorber and bolometer. The metamaterial, in conjunction with planar di ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  4. Multiplex Microsphere Assay for Botulinum Neutralizing Antibodies

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD11109

    Currently, the accepted standard experimental model for measuring protective efficacy against botulism is the Mouse Lethality Neutralization (MLN) assay. Botulism poisoning is a life threatening condition that is not only a public health concern, but could also be a potential biological weapon. With seven serotypes of botulinum neurotoxins, there is need for an alternative to the MLN assay due t ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  6. Handheld FT-IR/Photoacoustic Chemical Agent Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes development of the MP-100 handheld FT-infrared photoacoustic chemical agent detector, following a highly successful Phase I effort. Chemical attacks and accidents can be mitigated partially by cost-effective sensors. High priority programs will benefit from a sensor compliant to Joint Warning & Reporting Network (JWARN) standards. The device is ideally suited to ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
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