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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human Services
  2. Nanodroplet PCR Lab-Chip for Clinical Pathogen Detection

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Rapid and accurate detection and identification of pathogens is crucial for the effective management and treatment of infectious disease. While molecular diagnostic techniques including PCR are a promising approach for rapid and sensitive detection of pathogens, they suffer from a number of technical drawbacks which have slowed their acceptance in the clinic. ...

    SBIR Phase I 2005 Department of Health and Human Services
  3. 3 Dimensional Nano-Scale Reinforcement Architecture for Advanced Composite Structures

    SBC: 3TEX, Inc.            Topic: AF04T020

    Three-dimensional woven and braided fiber architectures provide important advantages to composites, including suppression of delamination, high damage tolerance, improved through-the-thickness properties, simplicity and cost-effectiveness of manufacturing complex composite structural components. However, in order to diversify applications and reach high volumes of utilization of these materials in ...

    STTR Phase II 2005 Department of DefenseAir Force
  4. Novel Structural Joining Concepts Using 3-D Textile Preforms and Composites

    SBC: 3TEX, Inc.            Topic: AF05248

    Strength and durability of commonly used bonded and bolted composite-to-composite and composite-to-metal structural joints suffer from sharp geometry variations, mismatch of elastic moduli, Poisson's ratios, coefficients of thermal expansion and thermal conductivity of the adherends, altogether causing high stress concentration and premature joint failure. The proposed work introduces several nove ...

    SBIR Phase I 2005 Department of DefenseAir Force
  5. Discovery of Peptide-based Bone Morphogenic Protein Mimetics

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this proposal, we present a novel approach for the identification and immobilization of a BMP mimetic. We plan to use phage display technology to identify peptides that mimic BMP-like signaling of the BMP receptors. These peptides will be linked to a previously identified high-affinity, collagen-binding peptide. The resulting hybrid molecule will allow contr ...

    SBIR Phase I 2005 Department of Health and Human Services
  6. Improved Orthopedic Implant Surface Coatings

    SBC: AFFINERGY, LLC            Topic: N/A

    Endosseous metallic implants are common alloplastic devices used in medicine and dentistry. The orthopedic and dental marketplace continues to grow and indications for implants are expanding. There is a perceived need to improve both the successful healing (osseointegration) and the long term outcome of implants by control of interfacial reactivity during healing and remodeling. The growth of know ...

    SBIR Phase I 2005 Department of Health and Human Services
  7. Electrochemical RT activity assay for measuring HIV load

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Phase I SBIR project Alderon Biosciences Inc. (ABI) proposes to demonstrate the feasibility of using electrochemical reverse transcriptase (eRT) assays for determinations of HIV viral load in clinical samples. Success will set the stage for Phase II development, FDA approval, and production of commercial kits using this advanced technology. The long-r ...

    SBIR Phase I 2005 Department of Health and Human Services
  8. Electrochemical Quantification of HCV RNA

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The National Institutes of Allergy and Infectious Disease have called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases. To meet this need, Alderon Biosciences Inc. (ABI) proposes to develop innovative, low-cost tests with sensitivity adequate for determining HCV viral load. Reliable and affordable HCV viral load t ...

    SBIR Phase I 2005 Department of Health and Human Services
  9. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  10. Advanced Commercially Available Inherently Radhard Primitive Cell Designs.

    SBC: American Semiconductor, Inc.            Topic: AF05018

    The Air Force Research Laboratory (AFRL), Military Satellite Communication (MILSATCOM), and National Aeronautics and Space Administration (NASA) have a current and future need for advanced commercially available inherently radhard primitive cell libraries to support new designs for satellites and other spacecraft. American Semiconductor Inc. proposes the use of double gated Flexfet technology for ...

    SBIR Phase I 2005 Department of DefenseAir Force

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