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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Delivery of pathogen trapping antibodies for vaginal protection

    SBC: MUCOMMUNE, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Despite immense efforts in behavioral interventions to promote safer sexual practices sexually transmitted infections STIs continue to be a pandemic worldwide Unfortunately there are no effective vaccines or microbicides for the majority of STIs A pathogen specific safe effective and discreet vaginal microbicide that does not require daily or sex associ ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. New Class of Bright Sharp Tunable Near Infrared Fluorophores for Flow Cytometry

    SBC: Nirvana Sciences, Inc.            Topic: R

    DESCRIPTION provided by applicant Polychromatic flow cytometry FC is one of the most powerful analytical techniques routinely used by both basic research and clinical diagnostics laboratories for the immunological categorization of cells Dyes used for FC typically exhibit broad fluorescent emission bands with full width at half maximum fwhm values of nm This limits the maximum numbe ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Medical Sensor Applications of Tunnel Magnetoresistance TMR

    SBC: KORONIS BIOMEDICAL TECHNOLOGIES CORP.            Topic: NIDCD

    DESCRIPTION provided by applicant Koronis Biomedical Technologies KBT proposes to develop a novel omnidirectional low power miniaturized hearing aid telecoil replacement module TCRM based on tunneling magnetoresistance TMR technology It has been reported that million Americans have hearing loss Hearing loss affects in Americans and in households Modern telecoils assist ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. The CellRaft AIR System Workflow Automation for Stem Cell Isolation and Recovery

    SBC: Cell Microsystems, Inc.            Topic: 200

    DESCRIPTION provided by applicant Stem cell research is an emerging field with the promise of creating dramatic new approaches for disease treatment and drug discovery The research and regenerative medicine market space for stem cells is one of the most dynamic areas in the life science industry today Globally the stem cell market is growing at a CAGR of and will reach an approximate ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Development of BIO as a MCM for lethal radiation pneumonitis fibrosis

    SBC: Humanetics Corporation            Topic: R

    Project Summary A significant need exists for effective medical countermeasures for radiation induced pneumonitis and pulmonary fibrosis associated with the delayed effects of acute radiation exposure Of great importance are countermeasures that can be distributed for use without medical supervision making orally effective countermeasures of high interest and importance To address this unmet ne ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. PTSD Monitoring System For Prolonged Exposure Therapy

    SBC: ACLARIS MEDICAL, LLC            Topic: 102

    DESCRIPTION provided by applicant Posttraumatic stress disorder PTSD affects of American adults over their lifetime and is estimated to cost the US over $ billion per year Prolonged Exposure PE is one of the most effective treatments for PTSD but under engagement poor adherence and dropout limit recovery for many patients Improved tracking and feedback of engagement level homew ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Memory Matters A Mobile Aid to Stimulate Reminiscing in Persons with Memory Loss

    SBC: MOAI TECHNOLOGIES, LLC            Topic: NIA

    DESCRIPTION provided by applicant This Phase II SBIR project will augment and investigate a digital game that was designed and successfully tested during a Phase I trial in a long term care facility The game called Memory Matters MM is designed to trigger reminiscing by persons with mild to moderate dementia related memory loss often caused by Alzheimerandapos s Disease by immersing thes ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Innovating Tablet Based Cognitive Assessment for CNS Disorders of Aging

    SBC: NEUROCOG TRIALS            Topic: NIA

    DESCRIPTION provided by applicant Aging populations have become a key target for therapeutics developers particularly for indications impacting cognitive function Conditions such as Alzheimerandapos s disease and vascular dementia affect the quality of life of aging Americans largely due to their impact on cognitive function with insufficient therapeutic options Recent reports indicate tha ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Novel Fast GPU Monte Carlo and Active Photonics Simulation Software for Predicting PDT Efficacy

    SBC: SIMPHOTEK, INC.            Topic: 102

    DESCRIPTION provided by applicant Photodynamic therapy PDT provides for standalone or intraoperative cancer treatment PDT provides a means to treat superficial and or residual disease while minimizing damage to underlying tissues and does not exhibit cumulative cell toxicities distinguishing it from radiation therapy As compared to radiotherapy treatment planning in PDT is often approa ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Compact Swept Near Infrared Light Source for Broadband Diffuse Optical Spectroscopic Imaging of Breast Malignancies

    SBC: Vixar Inc.            Topic: 102

    DESCRIPTION provided by applicant This project will develop swept wavelength laser light sources at several frequencies in the near infrared NIR While applicable to numerous applications the goal is to use these laser sources as an enabling technology for Diffuse Optical Spectroscopic Imaging DOSI a technique which allows noninvasive characterization of human tissue and can monitor and p ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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