Award Data

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

We propose to develop multiresolution representations and algorithms for synthetic terrain environments. They will be used for representing large terrain models as well dynamic and atmospheric simulations. Our ultimate goal is to increase the validity of the simulation by incorporating the multiple models at varying resolutions. We will use the OneSAF simulation Product Line Architecture Framework ...

Insensitive munitions (IM) design and testing for propulsion systems is hindered both by high test costs and the complexity of propellant responses to IM stimuli. Modeling and simulation tools for predictions of IM hazards are under development that characterize many of the pertinent phenomena, including damage sensitization to reaction and delayed-onset detonation. Such tools can provide many b ...

Maintenance on Army Tactical Power Systems (TPS's) is currently performed at regular intervals regardless of actual usage or operating conditions - wasting resources servicing systems that do not need maintenance, and missing opportunities to prevent catastrophic failures. The Army seeks to 1) improve maintenance efficiency and effectiveness by servicing systems based on actual usage and 2) imple ...

Infection in areas of bone injury are a serious consideration in the field of trauma surgery and orthopaedic medicine. The combination of regenerative medicine and controlled drug delivery offers great potential to improve on the current standard of care. Presently, bone infection secondary to osteomyelitis and non-union are treated in a two-stage protocol wherein the first step requires placeme ...

Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...

Conceputal prototype testing to improve web accessibility and make it cost-effective and attractive to non-technical audiences

The overall objective of this proposal is to characterize the molecular mechanism by which variable frequency microwave technology (VFM) inactivates bacterial spores. The long-term practical goal is to produce a device capable of eliminating contamination by microbial/viral/biological based biological warfare bioterrorism agents. Considerable scientific uncertainty exists regarding the molecular ...

ENVIRONMENTAL DIAGNOSTICS, INC. PROPOSED TO DETERMINE THE FEASIBILITY OF APPLYING ITS NEW INNOVATIVE HAPTEN TECHNOLOGY TO THE DEVELOPMENT OF IMMUNORECEPTORS FOR DETECTION AND ASSAY OF BIOLOGICAL TOXINS. THE NEW HAPTEN RECEPTOR TECHNOLOGY OVERCOMES PREVIOUS SCIENTIFIC LIMITATIONS AND TECHNICAL DIFFICULTIES IN DEVELOPING IMMUNOASSAYS FOR HIGHLYTOXIC, LOW MOLECULAR WEIGHT PROTEIN TOXINS. TO DATE, THE ...

THE PROJECT WILL BE DEVOTED TO SELECTING AN OPTIMUM CONFIGURATION AND RUNNING 1/4 SCALE MODEL TESTS OF A ROGALLO TYPE WING. THE WING WILL HAVE HIGHER THAN USUAL ASPECT RATIOS FOR ROGALLO WINGS, AND WILL BE AIR DEPLOYABLE. A CONTROL SYSTEM TO AUTOMATICALLY LAND THE VEHICLE WILL BE DEVELOPED. FINAL DESIGN OF A FULL SCALE VEHICLE WILL BE DELIVERED.