Award Data

This Phase-II SBIR proposal directly addresses the need to improve the size, weight and power, SWaP, of optical cryocoolers. In particular, the proposers will work toward increasing the efficiency of optical cryocoolers by incorporating cooling materials that require less input laser power to achieve a given heat lift. The new cooling materials will be high-purity crystals doped with active rare-e ...

Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

Effective collective protection fabrics must have a reliable closure system. During our Phase I Work Plan, Sigma-K began developing a Hermetic Textile Closure Hardware (HATCH) system. The HATCH combines both a magnetic and geometric self locking mechanism that will provide a hermetic seal when closed. Our current Phase I successes include developing self closing samples that can provide a hermetic ...