Award Data

Melioidosis and glanders are life-threatening illnesses caused by the bacteria Burkholderia pseudomallei and Burkholderia mallei, respectively. These gram-negative bacilli are endemic to Northern Australia and Southeast Asia, however endemic regions are expanding as surveillance improves. B. pseudomallei and B. mallei are classified as Tier 1 select agents for potential use in bioterrorism, largel ...

Burkholderia pseudomallei and Burkholderia mallei are highly pathogenic Gram-negative bacteria and the causative agents of melioidosis and glanders, respectively. These infections, which occur in humans and other animals, are endemic is wide regions of the developing world. Translational research regarding these pathogens is focused on developing new strategies to detect, treat and ideally protect ...

Currently, the United States Military encounters many scenarios where soldiers must enter hazardous areas, while maintaining isolation from contaminants such as chemical and biological agents as well as hazardous material exposure. This requires that the soldiers respiratory tract be isolated to prevent exposure to these contaminants. In order to accomplish this, the soldiers wear protective suits ...

Safe and efficient ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these limitations, we propose to develop and demonstrate a novel bioaerosol ionization and collectio ...

This proposal outlines Mainstreams successful Phase I feasibility demonstration related to the fabrication of hierarchical hybrid nanomaterials for oxygen storage vessels. These vessels exceed the volumetric and gravimetric storage capacity of an oxygen cylinder by 245% and 170%, respectively. Included in these storage density values is a solid-state oxygen regulation system that also enables comp ...

A development program is proposed for a design automation software package that enables the generation of complex surfaces, with user defined or automated definition of point charge and hydrophobic/hydrophilic properties, using DNA origami as a presentation substrate. Building upon Parabons existing software for DNA origami design, this project will result in software that can be used to design a ...

In Phase I RANCOR successfully demonstrated an innovative enabling humidity control technology to provide very low humidity air to water sensitive, fully reusable CO2 adsorbents. The use of adsorbents enables complete reusability/rechargability and reduces the total heat load on the SCBA to the point where ice or other cooling systems will no longer be required. In Phase II Paragon will introduce ...

SA Photonics is pleased to propose the development of the SENTRY hyperspectral situational awareness system for the detection of liquid chemical agents in the asymmetric terrorist warfare scenario. SA Photonics will be teaming with world renowned experts from its university partners for the development of the SENTRY system. Additionally, SA Photonics will be leveraging technology from numerous N ...

Physical Sciences Inc. (PSI) proposes to utilize an innovative LWIR hyperspectral technology coupled with advanced data processing algorithms for non-contact, standoff detection of liquid/solid contaminants on surfaces. The technology will address the US Army"s need for fast, on-the-move, non-contact detection of ground contamination during reconnaissance missions. The Phase I effort demonstrated ...

Protein manufacturing is of paramount importance to chemical and biological defense applications. Existing protein purification methods primarily rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermeasures to chemical and biological threats. To overcome these limitations, the overall goal of th ...