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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Multi-view, Photon Counting DXA Scanner for Quantitative Musculoskeletal Imaging

    SBC: QUANTUM MEDICAL METRICS, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): The fragility of osteoporotic bones is largely due to alterations in the underlying structural geometry. Research has demonstrated that it is possible to measure the mechanical geometry of human bones in vivo using dualenergy x-ray absorptiometry (DXA) scans. However DXA scanners are designed to measure bone mineral density (BMD) and not structural geometry. Th ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Targeting host response to DAMP for therapy of Rheumatoid Arthritis

    SBC: Oncoimmune Inc            Topic: NIAMS

    DESCRIPTION (provided by applicant): Rheumatoid arthritis (RA) is among the most common autoimmune diseases. The current treatment for RA is mainly by targeting tumor-necrosis factor (TNF). Despite the remarkable efficacy, significant portion of RA patients are not responsive to this class of drugs. Therefore, there is an urgent need to develop therapeutic that can complement existing therapeutic ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Serum GP88 biomarker as a surrogate marker for disease progression in breast canc

    SBC: A&G PHARMACEUTICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): 40,000 women die annually in the US as a result of breast cancer (BC). Although BC can be controlled if detected early, a significant number is not detected until later and these patients are treated using therapies tocontrol both primary tumor and micro-metastatic disease. Therapy response is monitored using imaging and clinical assessment. Failure to detect e ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Protease chain reactions for molecular analysis of cancer markers

    SBC: POTOMAC AFFINITY PROTEIN LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Our objective is to develop a protease chain reaction technology (ProCR) which will enable ultra- sensitive molecular detection. A protease chain reaction has four basic components: 1) a protease conjugated to a bindingmolecule, 2) an unconjugated protease, 3) an inhibitor protein which contains a proteolytic cleavage site and 4) a protease substrate which gene ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Physics-Based Head and Neck Surgical Simulation of Soft Tissue Manipulation

    SBC: SIMQUEST INTERNATIONAL, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): SimQuest LLC proposes to develop a physics-based head and neck simulator to enhance training of dental, endodontic, oral, maxillofacial, plastic, trauma, ENT, and other trainees and surgical educators. This Phase I workwill advance the state of the science in surgical education by establishing the foundation for a simulator that will greatly enhance surgical tr ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Ultrathin Intraoral 3D Camera

    SBC: XIGEN, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): Intraoral three-dimensional (3D) imaging capability promises to revolutionize traditional dental practice workflow by allowing chairside real-time 3D digital model acquisition without taking traditional impressions, thus facilitating speedy and accurate computer-aided-design (CAD) and computer-aided- manufacturing (CAM) of dental restorations at dentist's ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Oral care treatment for mobility-impaired patients

    SBC: Athena Environmental Sciences Inc            Topic: NIDCR

    DESCRIPTION (provided by applicant): Biofilm infections are a major cause of mortality and morbidity. Dental caries occur as a result of an infectious disease in the oral cavity that is characterized by localized demineralization of susceptible tooth surfaces. The onset of dental caries results from the formation of an oral biofilm or plaque. Oral biofilm build-up is prevented using mechanical (b ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. HazMatIQ LIVE eLearning_The Missing Link in HazMat Response Training

    SBC: MetaMedia Training International, Inc.            Topic: NIEHS

    DESCRIPTION (provided by applicant): MetaMedia will use the internet to deliver high quality, job-related pertinent hazardous materials and safety training to a large national responder audience at a low cost. Online training alleviates many problems facedby public safety professionals' training, allowing students to train on their schedule while on duty or at home, and with the ability to st ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. DNA Repair-on-a-Chip: Spatially Encoded Microwell Arrays

    SBC: TREVIGEN, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Human exposure to dangerous genotoxins is unavoidable, as DNA damaging agents are ubiquitous both in our environment and within our cells. DNA damaging agents and other genotoxins that arise from cellular metabolism, environmental sources or disease-related cellular defects contribute to cell death (e.g., neurodegeneration), gene mutations, gene rearrangements ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. DBillScan: A Camera Phone Based Currency Reader for the Visually Impaired

    SBC: LIMAGING LLC            Topic: NEI

    DESCRIPTION (provided by applicant): For this SBIR Limaging, LLC teams with researchers in Ophthalmology at the Wilmer Eye Institute at Johns Hopkins University to develop DBillScan, a camera phone based currency reader to identify U.S. dollar bills for the blind and visual impaired (VI). In many countries the currency is printed on different sizes of paper or with different tactile mars for peopl ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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