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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Brain Trauma Assessment System

    SBC: Active Signal Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): With over 1.5 million persons suffering head injury annually in the U.S., and approximately 50,000 dying from these injuries, a need exists for early direct assessment of brain injury. Currently, injuries must be inferred from Glascow Coma Scores (GCS), low blood pressure, and/or low pulse oximetry, but there is no direct method of measuring brain condition at ...

    SBIR Phase I 2003 Department of Health and Human Services
  2. Computer-aided decision model for interpreting breast MR

    SBC: Alan Penn & Associates Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop, evaluate and commercialize a computer-aided-diagnosis (CAD) system that supports an enhanced decision model for interpreting breast MR images. The proposed system will enable clinicians to more readily incorporate breast MR into their decision-making and patient care. The specific aim is to develop an integrated m ...

    SBIR Phase II 2003 Department of Health and Human Services
  3. Computer-aided decision model for interpreting breast MR

    SBC: Alan Penn & Associates Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop, evaluate and commercialize a computer-aided-diagnosis (CAD) system that supports an enhanced decision model for interpreting breast MR images. The proposed system will enable clinicians to more readily incorporate breast MR into their decision-making and patient care. The specific aim is to develop an integrated m ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Gestural Interfaces and Robotics for Rehabilitation

    SBC: Anthrotronix, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project examines the feasibility of using gestural interfaces technology and interactive robotics to facilitate motor development and functional mobility of children with cerebral palsy. Physical impairments such as cerebral palsy can significantly impact a child's development of normal motor patterns. Cerebral p ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. A REAL-TIME ASSAY FOR Gs PROTEIN-COUPLED RECEPTORS

    SBC: ANASPEC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): G protein-coupled receptors (GPCRs) are major drug targets for a wide spectrum of diseases including neurological diseases such as migraine, anxiety, psychosis, and schizophrenia Novel robust assay technologies are continuously demanded for GPCR targets to increase odds for leads generation in a large-scale compound screening. Activation of GPCRs results in cha ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. Novel Melanocortin Receptor 4 Agonist for Obesity

    SBC: ANASPEC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is a serious medical condition affecting an estimated 40 million people and contributing to 300,000 deaths annually in the U. S. The appropriate regulation of energy intake and expenditure relies on complex hypothalamic neurocircuitry. Two key components of this system include neuropeptide melanocortin and its G-protein coupled receptor, the melanocort ...

    SBIR Phase I 2003 Department of Health and Human Services
  7. Flexible NLP system for MEDLINE information extraction

    SBC: ARIADNE GENOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Small Business Innovation and Research Phase I project focuses on the development of the fully automatic system for extraction of the protein function information from MEDLINE abstracts and conversion it into a form of a conceptual graph. All existent protein function databases depend on human experts who cannot keep up with the exponential growth of prote ...

    SBIR Phase I 2003 Department of Health and Human Services
  8. Housekeeping Genes: Possible Antifungal Drug Targets?

    SBC: Athena Environmental Sciences Inc            Topic: N/A

    DESCRIPTION (provided by investigator): The occurrence of fungal infections has escalated significantly in recent years. Increases in the number of patients presenting with candidiasis and aspergillosis in particular, has been profound, especially in those immunocompromised by disease or therapies. Unfortunately, only a limited number of antifungal drugs are available for treatment of these and ot ...

    SBIR Phase I 2003 Department of Health and Human Services
  9. A Biological Assessment System for Cognitive Persistence

    SBC: BIOASSESSMENTS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The low frequency cardiac rhythm (LFCR) is an innovative, but underutilized, biological marker. The PI's studies show that LFCR is strongly associated with the state of cognitive persistence in controls. Cognitive persistence refers to the ability to remain on-task and inhibit impulsive off-task behavior. Additional preliminary data also suggest that children w ...

    SBIR Phase I 2003 Department of Health and Human Services
  10. Light Visor for Treating Jet Lag: Controlled Field Trial

    SBC: Bio-Brite, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Jet lag is a syndrome of behavioral, cognitive, and physical symptoms that result when travelers are exposed to a sudden shift of the day-night cycle. These symptoms impact on alertness and performance of airline and military personnel and the safety of the traveling public. They may also exacerbate medical and psychiatric illness, and frequent flyers may face ...

    STTR Phase I 2003 Department of Health and Human Services

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