List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel Targeted Therapy for Breast Cancer

    SBC: A&G PHARMACEUTICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Breast cancer remains one of the top three cancers to affect and cause mortality in women. Major shortcomings with current treatment are the high level of side effects and insufficient efficacy, particularly for patients with metastatic disease. Targeted cancer therapy is designed to treat only the cancer cells and minimize damage to healthy cells. These target ...

    SBIR Phase I 2007 Department of Health and Human Services
  2. Diagnostic protein array for respiratory infections

    SBC: AKONNI BIOSYSTEMS INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this project is to transition Argonne-developed intellectual property into the commercial marketplace, and develop a protein array for clinical surveillance and diagnosis of common respiratory infections, including influenza A, influenza B, parainfluenza (types 1-3), human respiratory syncitial virus (RSV), adenovirus (types A-f), SARS coronavi ...

    SBIR Phase I 2007 Department of Health and Human Services
  3. Integrated, on-chip RT-MME-PCR for influenza diagnostics; Phase 1 = sample prepar

    SBC: AKONNI BIOSYSTEMS INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Influenza viruses are highly contagious, segmented negative-sense RNA viruses that belong to the family Orthomyxoviridae, causing approximately 114,000 hospitalizations and 20,000 deaths annually. Several drugs are approved by the US Food and Drug Administration (FDA) for treating influenza infections, but successful treatment depends on administering these dru ...

    SBIR Phase I 2007 Department of Health and Human Services
  4. Treatment of diabetic gastroparesis with nitric oxide

    SBC: AMULET PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal will establish proof of concept for the use of nitric oxide (NO) as an effective treatment for diabetic gastroparesis. The NO will be delivered using Amulet's NORTECH nitric oxide releasing technology. NORTECH delivers NO in a predictable and controllable manner, and without the possibility of forming carcinogenic nitrosamines. NORTECH is uniquely ...

    SBIR Phase I 2007 Department of Health and Human Services
  5. Gestural Interfaces and Robotics for Rehabilitation

    SBC: Anthrotronix, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase II project is to develop robot-based content to target upper extremity movement therapy goals and evaluate the clinical efficacy of the CosmoBot Robotics System as a therapy intervention for children diagnosed with cerebral palsy, brain injury, and stroke. Cerebral palsy is the most prevalent and one of the three mo ...

    SBIR Phase II 2007 Department of Health and Human Services
  6. Development of Novel Bioprocess Platform for Rapid, Economical Production of Pept

    SBC: APC BIOTECHNOLOGY SERVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A novel bioprocess platform, involving synthesis of peptide and protein biopharmaceutical products as fusions with a synthetic "anchor" protein in bacteria, and subsequent proteolytic cleavage, will be developed. The unique features of the system allow for the economical production of large quantities of simple linear peptides, as well as complex, multi-compone ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. Long Term Storage and Precision Dispensing of Precious Liquids

    SBC: ARCHIVEX, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Precious liquid samples such as aqueous genomic DNA are the bedrock for immense efforts currently underway to better understand associations between disease phenotype and genotype. These efforts promise to pave the way to better prevention and treatment of human disease. Many laboratories maintain archives of thousands of such precious samples for years at a ti ...

    SBIR Phase II 2007 Department of Health and Human Services
  8. A Toxicological Knowledge Base Prototype

    SBC: ARIADNE GENOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): An efficient drug research and development process requires the in-depth understanding of the molecular, cellular and toxicological properties and mechanisms of a drug candidate. Relevant pieces of information are scattered among thousands of scientific publications, and bringing them together is becoming a bottleneck in the modern biomedical research and drug ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. Improved Bladder Cancer Therapy With Recombinant BCG

    SBC: BACILLIGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this product development plan is to develop a recombinant bacille Calmette-Gu rin (rBCG) strain that displays reduced toxicity and improved cancer immunotherapeutic properties. We believe that we can achieve this goal by altering both the tissue-binding and proinflammatory properties of BCG. The central hypothesis of this project is that ...

    SBIR Phase I 2007 Department of Health and Human Services
  10. Bioscience Research Integration Software Platform

    SBC: BIOFORTIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The need to investigate and understand all elements of biological information pertinent to disease is more clearly evident now than ever before. However, the avalanche of non-integrated data produced by today's technologies prevents scientists from effectively reducing these data to meaningful discoveries. As a result, the vast bulk of data collected through ...

    STTR Phase II 2007 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government