Award Data

THE SURFACE PLASMON RESONANCE PHENOMENON WILL BE EXPLORED TO DEVELOP A QUANTITATIVE, SENSITIVE, ASSAY SYSTEM FOR REPRODUCTIVE HORMONES OF CLINICAL INTEREST. THE APPROACH CAN ATTAIN, WITH RELATIVELY INEXPENSIVE INSTRUMENTATION, A SENSITIVITY LIMIT COMPARABLE TO EXISTING ASSAY METHODOLOGIES, WITHOUT THE USE OF DYES, RADIOISOTOPES OR ENZYMES FOR SPECIFIC SIGNAL GENERATION. PART OF THE PHASE I RESEARC ...

WE WILL DEVELOP A NEW DIAGNOSTIC TEST TO SUBSTANTIALLY IMPROVE THE DEFINITIVE DIAGNOSIS OF PE. PE IS A COMMON DISEASE OF PREGNANT WOMEN AFFECTING THE MOTHER, FETUS, AND NEONATE. PE IS CHARACTERIZED BY THE ONSET OF HYPERTENSION, PROTEINURIA AND EDEMA AFTER THE 20TH WEEK OF GESTATION IN PREVIOUSLY NORMOTENSIVE WOMEN. RECENT STUDIES SUGGEST THAT THE PRIMARY PATHOGENESIS OF THIS DISORDER IS UTEROPLACE ...

FOR ROTORCRAFT IN A NAP-OF-THE-EARTH (NOE) FLIGHT REGIME, COLLISION WITH WIRES PRESENTS A SIGNIFICANT THREAT TO SAFETY. WIRE DETECTION AND AVOIDANCE IS THUS AN IMPORTANT PART OF SAFE NOE GUIDANCE. WIRE DETECTION CAN BE DIFFICULT:WIRES ARE OFTEN NOT STRONGLY SPATIALLY EVIDENT, DANGEROUS WIRES OFTEN OCCUR AT THE FOCUS-OF-EXPANSION (FOE), THERE IS OFTEN SIGNIFICANT BACKGROUND CLUTTER AND NOISE, AND T ...

THE CONTRACTOR WILL DETERMINE THE FEASIBILITY OF USING SILICON AND TANTALUM BASED INORGANIC POLYMER COATINGS FOR PASSIVATING NEURAL PROSTHETIC IMPLANTS. THE CONTRACTOR WILL DETERMINE THE FEASIBILITY OF USING SILICON AND TANTALUM BASED INORGANIC POLYMER COATINGS FOR PASSIVATING NEURAL PROSTHETIC IMPLANTS.

NETCON (NEW THERMIONIC CONVERTER) IS A NEW IDEA FOR AN ADVANCED POWER CONVERSION SYSTEM. THE EMITTERS ARE TYPICALLY 0.5 CM IN DIMENSION. THE EMITTER AND COLLECTOR ARE SEPARATED BY LESS THAN 0.5 MILS ( 12 MU M), WITH OPERATION IN THE QUASI-VACUUM (UNIGNITED) MODE. THE INTERELECTRODE GAP IS SET BY THE THERMAL EXPANSION OF A CERAMIC PEDESTAL SUPPORTING THE EMITTER. HEAT TRANSPORT TO THE EMITTER IS BY ...

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THE PROPOSED R&D WILL ESTABLISH A NEW CAPABILITY OF LIGHT-ELEMENT X-RAY FLUORESCENCE ANALYSIS THAT SUPPORTS THE ACCURATE QUANTITATIVE MEASUREMENT OF THE BIOGENIC ELEMENTS. THE BASIS FOR THIS NEW CAPABILITY IS A CLASS OF INNOVATIVE X-RAY WAVELENGTH-DISPERSIVE OPTICAL COMPONENTS KNOWN AS LAYERED SYNTHETIC MICROSTRUCTURES (LSM). THESE COMPONENTS, WHEN COMBINED WITH EXISTING ENERGY-DISPERSIVE DETECTOR ...

THE DEVELOPMENT OF AN AUTOMATED TEST METHOD TO EXTRACT CMOS VLSI CIRCUIT PARAMETERS TO ASSESS HOT-ELECTRON RELIABILITY AND RADIATION HARDNESS IS PROPOSED. THE INSTRUMENT, COMBINED WITH STANDARDIZED TEST CHIPS, WOULD BE UNIQUELY SUITED FOR QUALIFICATION OF LOW-VOLUME ASIC CIRCUITS FOR SPACEBOURNE APPLICATIONS. THE PROPOSED CONCEPTINCLUDES THE DEVELOPMENT OF AUTOMATED TRANSFER OF TEST DEVICES BETWEE ...

WE WILL DEVELOP AND DEMONSTRATE A NEW HARDWARE ARCHITECTURE FOR X-RAY MAMMOGRAPHY SYSTEMS THAT WILL PROVIDE ENHANCED DIAGNOSTIC PERFORMANCE, PRODUCING HIGHER QUALITY IMAGES AT LOWER PATIENT DOSE AND LOWER EXAMINATION COST. THE PROJECT WILL IMPLEMENT A NOVEL LINE-SCAN EXPOSURE METHOD THAT ENHANCES THE SIGNAL-TO-NOISE PERFORMANCE OF THE SYSTEM, IMPROVING ITS SMALL-OBJECT AND DIFFUSE-OBJECT DETECTABI ...

A NOVEL PHYSIOLOGIC SKIN MODE HAS BEEN DEVELOPED UTILIZING HUMAN NEONATAL DERMAL FIBROBLASTS CULTURED ON A BIODEGRADABLE, POLYGLYCOLIC OR POLYGLACTIC ACID, MESH. THE PROLIFERATING CELLS STRETCH ACROSS THE MESH OPENING AND SECRETE NATIVE GROWTH FACTORS, COLLAGENS AND OTHER EXTRACELLULAR MATRIX PROTEINS TO PRODUCE AN IN VITRO HUMAN DERMAL TISSUE. HUMAN KERATINOCYTES CAN ALSO BE CULTURED ONTO THIS DE ...