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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of an Orally Available Therapeutic for Neutralizing C. difficile Toxin B

    SBC: NECTAGEN INC            Topic: NIAID

    Infection with the bacterium C. difficile is the most common and increasingly prevalent cause of diarrhea. In the United States, cases of C. difficile infection (CDI) are estimated to number 500,000 annually and to result in an estimated 15,000 to 30,000 deaths. The cost of these cases is thought to exceed $4.8 billion annually. CDI continues to cause discomfort, serious illness and sometimes deat ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. STARTUP Central

    SBC: CONTINUUM EDUCATIONAL TECHNOLOGIES, PBC            Topic: 500

    PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Research Translation by Uplifting Participants for the Central IDeA State Region (STARTUP Central) program to stimulate technological innovation in the IDeA state regions by addressing the entrepreneurial educational needs o ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Integration of non-invasive deep tissue microwave thermometry in the VectRx hyperthermia device in a transgenic liver tumor pig model

    SBC: NeoTherma Oncology Inc.            Topic: 102

    Project Summary/Abstract NeoTherma Oncology (NTO/www.neothermaoncology.com) has developed a novel non-invasive medical device that delivers mild hyperthermia (HT) loco-regionally as adjuvant therapy to standard of care treatment of abdominal deep-seated tumors. The VectRx™ device, designated “Breakthrough” by the FDA, has demonstrated its ability to safely heat abdominal organs (pancreas, li ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Oral Dissolvable Strips (ODS) as new pediatric and adult delivery mode of therapy for latent tuberculosis

    SBC: OAK THERAPEUTICS INC            Topic: NIAID

    PROJECT SUMMARY Tuberculosis (TB) remains one of the major sources of mortality from infectious diseases worldwide. In 2021 an estimated 6.4 million were newly diagnosed with TB globally, approximately 10.6 million fell ill from it, and 1.4 million died from the disease. Of those who died from the disease, 54% were men, 32% women, and 14% were children aged lt15 years. TB is also a leading cause o ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Functionalized Multi-Modal Tetrode Arrays for Real-Time, Site-Specific Neurochemical Monitoring

    SBC: Pinnacle Technology, Inc.            Topic: 101

    ABSTRACT The goal of this proposal is to develop a multimodal, multianalyte sensor system including wired and wireless electronics and software. This new suite of tools will enable simultaneous recording of amperometric sensors (glutamate, glucose, lactate, choline, and/or oxygen), electrophysiology, and fast-scan cyclic voltammetry (biogenic amines) in conscious, freely moving rodents. The propos ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Piezoelectric Intramedullary Nail for Enhanced Fracture Healing

    SBC: EVOKE MEDICAL LLC            Topic: NIAMS

    PROJECT SUMMARY The objective of this Phase I SBIR is to develop a modular piezoelectric intramedullary nail for enhance fracture healing and post-operative data collection. Evoke Medical’s core technology is to create human- powered implantable devices that utilize piezoelectric materials to generate load-induced power. That power can then be used for various purposes: electrical stimulation of ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. The Rapid-Production of the High-Performance and Affordable Cadmium Telluride and Cadmium Zinc Telluride for Medical Imaging Applications.

    SBC: RADIATION DETECTION TECHNOLOGIES, INC.            Topic: NIBIB

    1 The high spatial-resolution and energy-resolution of cadmium zinc telluride (CZT) and cadmium telluride2 (CdTe), compared to that of scintillators, offers superior image quality in Nuclear medicine and X-ray3 imaging applications, i.e. SPECT, PET, CT, Bone Densitometry, Oncology, Dental imaging, Airport4 security, etc. CZT and CdTe remain the desired choice for room-temperature radiation detecti ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a comprehensive suite of research-backed, integrated educational tools to inspire, educate, train, and support academic entrepreneurs in the commercialization of university research.

    SBC: CONTINUUM EDUCATIONAL TECHNOLOGIES, PBC            Topic: 500

    PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Research Translation by Uplifting Participants for the Central IDeA State Region (STARTUP Central) program to stimulate technological innovation in the IDeA state regions by addressing the entrepreneurial educational needs o ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a tumor-retentive immunostimulant as adjunct therapy for solid tumor cancers

    SBC: KINIMMUNE, INC.            Topic: NCI

    PROJECT SUMMARY/ABSTRACT Cancer immunotherapy activates the host immune system to seek and destroy cancer cells. Checkpoint inhibitors block immunosuppressive signals, thereby ‘releasing the brakes’ of the immune system. Solid tumors, however, typically do not respond well to checkpoint inhibitors. They are only effective in the 20-30% patients with an already immunologically ‘hot’ tumor. ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. MWA verification system for improved confidence in treatment outcomes

    SBC: Precision Microwave Inc.            Topic: NCI

    PROJECT SUMMARY/ABSTRACTThis SBIR Phase I application aims to investigate a novel intra-procedural feedback mechanism for microwave ablation (MWA) procedures used for the thermal treatment of localized cancer. Although MWA provides a minimally invasive, low cost, outpatient therapy that has comparable outcomes to the gold standard surgical resection for small tumors, local recurrence rates remain ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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