Award Data

This Small Business Innovation Research (SBIR) Phase I project proposes to investigate the feasibility of fabricating large-aperture, periodic ferroelectric domain gratings for quasi-phase matched laser frequency conversion. The key innovation in this effort is the use of low temperature hydrothermally grown potassium titanyl phosphate (LTH-KTP) as the nonlinear optical substrate material. Using L ...

Infectious disease is a serious threat to military personnel in operations in third world countries. The ability to rapidly diagnose disease is critical to initiate treatment and to reduce troop mortality. This research addresses the DoD need to adaptstate-of-the-art technology to develop a rapid, field-usable assay capable of diagnosing scrub typhus infection. ChelaTech has developed new compo ...

The need for a rapid, reliable needle free delivery system for Hu BCHE bioscavengers is identified. The critical medical and design issues involved are presented. A needle free jet injection system is detailed. The Phase I effort comprises detailedpharmacokinetic studies and preliminary and detailed device design. The fabrication of a size appropriate injector for test rodents will also be underta ...

Phase II will focus on the design and development of a prototype needle-free injection system for administering BChE enzyme into humans to provide protection against chemical warfare agents. The Phase I proof-of-concept demonstrated the accelerateddelivery of BChE into the circulatory system using needle-free injection. The second phase of this project will consist of the following three tasks: ...

This Small Business Innovation Research (SBIR) Phase II project aims to develop a novel process for in-situ bioremediation of methyl tert-butyl ether (MTBE) in groundwater. The Environmental Protection Agency (EPA) considers MTBE a potential human carcinogen. Currently, MTBE's Maximum Contaminant Level (MCL) in drinking water has been set for 18 parts per billion. It is estimated that the cost of ...

This Small Business Innovation Research (SBIR) Phase II project aims to develop a process for enhancing the nutritional value of soybeans to replace fishmeal as the primary ingredient in farmed trout and salmon feed. Fishmeal creates environmental and economic constraints for the aquaculture industry. Plant-derived proteins are a good alternate feed source, but do not meet the nutritional requir ...

This Small Business Innovation Research Phase I project will demonstrate the feasibility of an innovative, environmentally benign, enzymatic catalyst process and an advanced reactor design for the production of silicon esters from various feedstocks. All current processes for making silicon esters are either using expensive rare earth metal as catalysts or using halogen elements containing compoun ...

This Small Business Innovation Research Phase II (SBIR) project will develop and demonstrate a novel prototype solvent extraction (SX) device, which, by virtue of its highly uniform shear and mixing intensity, has the potential to supplant existing SX units in terms of extraction and phase separation rates. The technical approach of the Phase II project is as follows: 1.) Develop performance and s ...

This Small Business Innovation Research Phase II (SBIR) project will develop and demonstrate a novel prototype solvent extraction (SX) device, which, by virtue of its highly uniform shear and mixing intensity, has the potential to supplant existing SX units in terms of extraction and phase separation rates. The technical approach of the Phase II project is as follows: 1.) Develop performance and s ...

Many Department of Defense (DoD) sites are contaminated with contaminants of concern (CoCs) that are hazardous to humans and the environment requiring novel remediation strategies. MSE Technology Applications, Inc. and the Center for Biofilm Engineering(Montana State University) propose this Phase I STTR to develop novel, biofilm-based, remediation technologies for in situ and ex situ bioremediati ...