Award Data

This Small Business Innovation Research Phase II project focuses on the development of new pharmaceutical agents to selectively enhance tumor imaging using gallium 67. A photo-degradation product of nifedipine, nitrosipine, has been found to selectively enhance the uptake of Ga67 by tumor cells. A specific derivative of nitrosipine has an even better selective uptake of the radioactive imaging age ...

This Small Business Innovation Research Phase I Project will advance Relational Bayesian Modeling (RBM) technology, with specific focus on Information-based Technology applications in electronic commerce, especially customer and application-system behavior modeling. Relational Bayesian modeling combines recent advances in graphical statistical modeling with modern relational and object-oriented da ...

This Small Business Innovation Research Phase I project will develop a relational Bayesian modeling framework for automated discovery of tamporal and spatial scale in ecological modeling. Scale resolution and cross-scale articulation are key problems in scientific model development, especially for complex ecosystem-scale and mixed human-natural systems modeling. Modeler's facilities for automatic ...

This Small Business Innovation Research (SBIR) Phase II project aims to develop a novel process for in-situ bioremediation of methyl tert-butyl ether (MTBE) in groundwater. The Environmental Protection Agency (EPA) considers MTBE a potential human carcinogen. Currently, MTBE's Maximum Contaminant Level (MCL) in drinking water has been set for 18 parts per billion. It is estimated that the cost of ...

This Small Business Innovation Research (SBIR) Phase I project will develop new surface derivatized reactive nanoparticles. These nanoparticles are expected to be highly active adsorbents and should be important in a number of applications. In the project, attention will be focused on preparing nanoparticles containing Lewis acid or base centers. The chemical modification involves introducing Lew ...

This Small Business Innovation Research (SBIR) Phase II project will develop a new generation of fluorescence amplifying reagents based on poly (phenylene ethynylene (PPE)) nanoparticles. Because of the role of the amplifying polymer in the enhanced sensitivity of these compounds, these compounds are called Amplimer reagents. The project will develop and launch two types of Amplimer reagents: mic ...

This Small Business Innovation Research (SBIR) Phase II project will develop a new generation of fluorescence amplifying reagents based on poly (phenylene ethynylene (PPE)) nanoparticles. Because of the role of the amplifying polymer in the enhanced sensitivity of these compounds, these compounds are called Amplimer reagents. The project will develop and launch two types of Amplimer reagents: mic ...

This Small Business Innovative Research (SBIR) Phase II project is to develop a novel material to enable improved performance of surface enhanced Raman spectroscopy (SERS). Availability of this material could result in the manufacture of pollution monitoring, industrial process monitoring, and defense-related products for the identification and quantification of analytes of importance to these mar ...

This Small Business Innovation Research Phase I project aims to tailor the low cost single-walled carbon nanotube/silica composite, produced a unique cobalt-molybdenum catalyst system (CoMoCATtm) method, for use as uniform, reliable, and cost-effective nanotube emitters. Preliminary results have shown that composites prepared from purified single-walled carbon nanotubes and dielectric nanoparticl ...

This SBIR project will develop an integrated fire modeling software package for use in building design and accident analysis. Modeling fires using a rigorous, scientific approach makes it possible to predict the course of an evolving fire and its impact on the building occupants, contents, and structure. The software will help designers implement new fire safety codes and standards that allow the ...