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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Site Directed Thrombolytic Agent

    SBC: AURAZYME PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Clot formation and dissolution are essential to human survival. Abnormal clot formation and occlusion of blood vessels of the heart, lung, brain, and peripheral circulation can result in death, incapacitation, and limb amputation. Rapid treatment with thrombolytic agents to dissolve clots and restore blood flow is a means to minimize morbidity and mortality i ...

    SBIR Phase I 2003 Department of Health and Human Services
  2. Ovalbumin locus BACs for expression of biotherapeutics

    SBC: AviGenics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): With a daily production capacity of two grams of protein per egg, the chicken ovalbumin gene locus has the potential to synthesize large amounts of biopharmaceutical proteins into the eggs of transgenic hens. This phase I SBIR project will test the feasibility of using large expression constructs, based on the complete 200 kilobase chicken ovalbumin gene locus, ...

    SBIR Phase I 2003 Department of Health and Human Services
  3. Casein Coated CAP Particles for Oral Insulin Delivery

    SBC: BIOSANTE PHARMACEUTICALS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Parenteral administration of insulin via the subcutaneous route is the only commercially available therapy to treat insulin-dependent diabetes mellitus. Multiple daily injections are required to manage and maintain blood glucose control due to its relatively short duration of action (4 to 8 hours). Oral insulin would provide an attractive alternative. However, ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Indoor Orientation and Wayfinding Aid for Vision Loss

    SBC: CHARMED TECHNOLOGY            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of the proposed research is to develop a product that increases the functional independence and quality of life of both older and younger people with vision loss by giving them a simple means of 1) orienting to and navigating through indoor spaces, 2) identifying office names and numbers in public buildings, 3) identifying products and pricing infor ...

    SBIR Phase I 2003 Department of Health and Human Services
  5. Ultrasonic Cryoconcentration of Human Plasma

    SBC: CryoFacets, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Plasma is of vital importance for direct transfusion and the manufacture of pharmaceuticals. Most plasma is frozen before such uses, however, during the freezing process, there is unavoidable, uncontrolled cryoconcentration of the plasma solutes The goal of this project is simply to control this universally accepted process. First, ultrasound is applied to enha ...

    SBIR Phase I 2003 Department of Health and Human Services
  6. N/A

    SBC: CYKE, INC.            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services
  7. N/A

    SBC: CYKE, INC.            Topic: N/A

    N/A

    SBIR Phase II 2003 Department of Health and Human Services
  8. N/A

    SBC: CYKE, INC.            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human Services
  9. Multimedia Teacher Training For Community Building

    SBC: EDGE ENTERPRISES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this Phase I project is to produce and pilot test the feasibility of learner-managed professional-development packages for teachers to use to learn how to create safe, supportive learning communities in their classrooms to enable students to learn the necessary social and cognitive skills to maintain ...

    SBIR Phase II 2003 Department of Health and Human Services
  10. Multimedia Writing Strategy Instruction for LD Students

    SBC: EDGE ENTERPRISES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this Phase I project is to test the feasibility of using an interactive multimedia format for instructing students with learning disabilities in writing strategies. To evaluate the feasibility of this type of instruction, an instructional program for teaching four punctuation rules and the strategies associated with those rules will be designed a ...

    SBIR Phase I 2003 Department of Health and Human Services

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