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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. C-arm Fluoroscopy for Prostate Brachytherapy

    SBC: BURDETTE MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A technique is proposed for the development of an intraoperative, 3-dimensional registration of C-arm fluoroscopic images with spatially-registered ultrasound visualization and implant guidance of radioactive implants and on-line implant assessment during the procedure for treatment of prostate cancer. With present techniques using transrectal ultrasound guidan ...

    SBIR Phase I 2003 Department of Health and Human Services
  2. High Power III-Nitride Heterojunction Field-Effect Effect Transistor Development

    SBC: III-N Technology, Inc            Topic: N/A

    The research proposed here is built on the recent successful fabrication of metal oxide semiconductor heterjunction field effect transistors (MOS-HFETs) based on AlGaN/GaN heterostructures with very high drain-current-driving and gate-control capabilitiesas well as unprecedented high breakdown voltages by the P.I.s research group at Kansas State University. III-nitride HFETs have great promises i ...

    SBIR Phase I 2003 Department of DefenseMissile Defense Agency
  3. Design & Synthesis of Novel Agents to Treat Amyloidosis

    SBC: Advanced Life Sciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The major goal of our proposed project is to advance the development of novel compounds for the treatment of amyloidosis and other protein aggregation diseases. Preliminary work demonstrated that two chalcones inhibited amyloid fibril formation, in vitro, and that further work is warranted. The amyloid diseases that arise from nonimmunoglobulin proteins includ ...

    SBIR Phase I 2003 Department of Health and Human Services
  4. Potential Brain Therapeutics

    SBC: AMERICAN BIOTECHNOLOGY RESEARCH CORP            Topic: N/A

    DESCRIPTION (provided by applicant): Use of botanical products such as exogenous antioxidants has gained considerable momentum in the last few years in therapy of human degenerative diseases. Among these antioxidants, tumeric, neem, guggul, alpha-tocopherol, Beta-carotene, and ascorbic acid have been shown to have a special relevance in maintaining the redox e ...

    SBIR Phase II 2003 Department of Health and Human Services
  5. Development of HTS Buffer Layers Using the ECONO Process

    SBC: APPLIED THIN FILMS, INC.            Topic: N/A

    Under Phase I effort, Applied Thin Films, Inc. (ATFI) discovered a new process to deposit oxide buffer layers for HTS coated conductors that is economical, scalable, and has demonstrated excellent performance with YBCO films (current densities of 1MA/cm2). The process is called ECONO (Epitaxial Conversion to Oxide via Nitride Oxidation) which is now being considered as the primary contender for t ...

    SBIR Phase I 2003 Department of DefenseAir Force
  6. Development of HTS Buffer Layers Using the ECONO Process

    SBC: APPLIED THIN FILMS, INC.            Topic: N/A

    Under Phase I effort, Applied Thin Films, Inc. (ATFI) discovered a new process to deposit oxide buffer layers for HTS coated conductors that is economical, scalable, and has demonstrated excellent performance with YBCO films (current densities of 1MA/cm2). The process is called ECONO (Epitaxial Conversion to Oxide via Nitride Oxidation) which is now being considered as the primary contender for t ...

    SBIR Phase II 2003 Department of DefenseAir Force
  7. High Emissivity Protective Cerablak Coatings for Metallic TPS

    SBC: APPLIED THIN FILMS, INC.            Topic: N/A

    The proposed effort relates to the use of Cerablak?, an amorphous-based black oxide material, as a coating for protection of metallic thermal protection systems (TPS) to be used in reusable launch vehicles (RLVs). This material shows potential to be a coating that meets all of NASA?s requirements for TPS protection in a single material system. The basic technical requirements for a coating to prot ...

    SBIR Phase I 2003 National Aeronautics and Space Administration
  8. Cerablak Matrix CMCs for Next Generation Radomes

    SBC: APPLIED THIN FILMS, INC.            Topic: N/A

    In this Phase I SBIR project, a low-cost oxide-oxide interface coating-free ceramic matrix composite (CMC) will be developed for radomes for next-generation high speed missiles. The innovative and key component of the CMC is a newly patented matrixmaterial (CerablakT) based on aluminum phosphate compositions. The key properties of CerablakT relevant to radome applications is its low dielectric c ...

    SBIR Phase I 2003 Department of DefenseNavy
  9. Optical Trapping

    SBC: Arryx, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Manipulation of objects on a microscopic scale can be done conveniently with a device known as a laser or optical tweezers. While laser trapping was originally devised for trapping Rayleigh particles (i.e. particles much less than the wavelength of the incident light) it's ability to manipulate biological particles such as macromolecules, viruses, microtubul ...

    SBIR Phase II 2003 Department of Health and Human Services
  10. Molecular Manipulation with a Holographic Laser Tweezers

    SBC: Arryx, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Manipulation of objects on a microscopic scale can be done conveniently with a device known as a laser or optical tweezers. While laser trapping was originally devised for trapping Rayleigh particles (i.e. particles much less than the wavelength of the incident light) it's ability to manipulate biological particles such as macromolecules, viruses, microtuble ...

    SBIR Phase I 2003 Department of Health and Human Services

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