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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Clinical Human Cell Production System for Broad Use
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): As a result of growing evidence of their therapeutic potential in cancer, infectious diseases, and tissue repair, there is an enormous increase in the research and discovery of cell-based medical treatments that require cultured cells. A large unmet need exists for a cost-effective system that will facilitate the development of clinical cell production capabil ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Enhanced Tumor Antigen Priming of Dendritic Cell Vaccine
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by the applicant): Dendritic cells have been shown to initiate, regulate, and direct cytolytic T-cell-mediated immune responses against tumor antigens in human patients. Recent clincal trials have demonstrated induction of clinically significant immune responses against malignant diseases using DCs primed ex vivo with autologous tumor antigens including tumor cell lysates. E ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Automated Perfused Culture Process for Adult Stem Cells
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Adherent mesenchymal cell populations derived from bone marrow (BM) have the capability of differentiating into multiple cell lineages in vitro and in vivo. The potential use of these populations, referred to as marrow stromal cells (MSC), in clinical applications to treat nonhematopoietic disorders is being intensely investigated. Ex vivo expansion is being us ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Clinical-scale Production of Osteoprogenitor Cells
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Due to morbidity and limited amounts of material, alternatives to autologous grafts for bone repair are desirable. Mixtures of marrow stromal cells (MSC) and carrier matrices are known to augment bone repair. Increasing the number of MSC through ex vivo expansion may significantly increase the amount and rate of new bone formation. In this proposal, the abilit ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
Automated Large-Scale Production of Endothelial Cells
SBC: Aastrom Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Treatment of ischemia by administration of bone marrow (BM)-derived endothelial progenitor cells (EPC) or ex vivo expanded EPC populations has been shown to enhance vascular regeneration in animal models and in clinical trials. For cell therapy to be practical in a clinical setting, simple, efficient, GMP compliant methods for cell production are needed. Aastro ...
SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health -
SBIR Phase I: Knowledge-Based Adaptive Software Development Methodologies
SBC: Adaptive Process Technologies Topic: N/AThis Small Business Innovative Research Phase I project builds on a research program investigating the design of process-based software development tools and methodologies. The project will develop a next generation of this software that supports the creation, refinement, and adaptation of software development methodologies in a principled manner while preserving the need for rapid innovation. Th ...
SBIR Phase I 2003 National Science Foundation -
High Power III-Nitride Heterojunction Field-Effect Effect Transistor Development
SBC: III-N Technology, Inc Topic: N/AThe research proposed here is built on the recent successful fabrication of metal oxide semiconductor heterjunction field effect transistors (MOS-HFETs) based on AlGaN/GaN heterostructures with very high drain-current-driving and gate-control capabilitiesas well as unprecedented high breakdown voltages by the P.I.s research group at Kansas State University. III-nitride HFETs have great promises i ...
SBIR Phase I 2003 Department of DefenseMissile Defense Agency -
Synthetic Aperture Mobile Communications (SARCOM)
SBC: ADVANCED MODULAR POWER SYSTEMS Topic: N/AImprovements in channel capacity (i.e. bit rate) of mobile communication systems are important for extending their range and data throughput capabilities for current military and civilian applications and enable a number of new, highly marketable,applications. The objective of the program is the design, fabrication, and demonstration of an inexpensive, lightweight, 2-way (transmit/receive) mobile ...
SBIR Phase I 2003 Department of DefenseArmy -
Personal Monitor to Detect Exposure to Toxic Agents
SBC: ADVANCED SENSOR TECHNOLOGIES, INC. Topic: N/ADESCRIPTION (provided by applicant): Advanced Sensor Technologies, Inc. (AST) proposes to continue its NIH funded Phase I efforts to develop a completely automated miniaturized device capable of monitoring different types of cholinesterases from a single drop of whole blood to determine the degree of exposure of an individual to organophosphate (OP) compounds or carbamates. This device will be ame ...
SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health -
Non-Invasive, Continuous, Transdermal Glucose Monitor w/Actuator Control
SBC: ADVANCED SENSOR TECHNOLOGIES, INC. Topic: N/AAST is developing a non-invasive methodology to continuously monitor blood glucose concentration. As opposed to employing near infrared spectroscopy, which suffers from limitations of sensitivity, stability, and repeatability, AST employs directmeasurement of glucose, via amperometric sensors, from minute amounts of interstitial fluid obtained transdermally. AST's miniature transdermal sampling ...
SBIR Phase II 2003 Department of DefenseOffice of the Secretary of Defense