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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Development of a serotype-independent vaccine based on Salmonella T3SA proteins

    SBC: INTEGRATED ANIMAL RESEARCH LLC            Topic: 83

    Salmonella is a bacteriathat causessevere stomach and gut distressinpeople andis the leading cause of food-borne illnesses resulting in hospitalization and death in the US. The resulting economic losses caused bythisbacteriain the livestock industry are staggering with much of the loss attributed to recalls, permanent disruption of the gut lining impairing nutrient absorption, and necessary cullin ...

    SBIR Phase I 2016 Department of Agriculture
  2. New Technology with Miniaturized Handheld Grain Combine for Eliminating Increasing Costs of Outdated Practices for Pre-Harvest Sampling

    SBC: Windcall Manufacturing, Inc.            Topic: 812

    Small and mid-sized farmers, custom harvesters, and universities lose millions of dollars annually to antiquated methods of moisture sampling grain prior to harvest. In 1963, the USDA standardized electronic moisture sampling. Today, all U.S. grain terminals/elevators are required to use electronic moisture sampling machines that are calibrated and inspected to USDA standards.Problem: Efficiently ...

    SBIR Phase I 2016 Department of Agriculture
  3. Use of nutrient rich insect base to create pasta and rice mimicking food products

    SBC: BUGEATER LABS INC            Topic: 85

    The global population is expected to reach 9.7 billion people by 2050 with food demand to increase by 70% during that time (van Huis, A. et. al, 2015 and Shockley, 2014). Nearly 200 million children worldwide suffer from malnutrition with the World Health Organization estimating that 54% of child mortality is the result of malnutrition (Shockley, 2014). With land and water use already stressed wit ...

    SBIR Phase I 2016 Department of Agriculture
  4. A multispectral imaging system for real-time prediction of beef tenderness and USDA grades

    SBC: Goldfinch Solutions, LLC            Topic: 85

    Beef tenderness is the most important trait influencing consumer satisfaction. Currently there is no method for real-time classification of beef by tenderness. Current beef marketing is based on USDA quality grades (Prime, Choice, and Select). Therefore, the beef industry needs an integrated system that can simultaneously predict beef tenderness and also USDA grades. In the Phase I study, we succe ...

    SBIR Phase II 2016 Department of Agriculture
  5. Development of an Osteoinductive Spinal Fusion Implant for Enhanced Fusion Rates

    SBC: Evoke Medical, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant The objective of this Phase I STTR research is to develop and test osteoinductive lumbar spinal fusion implant prototypes made using materials technology developments discovered by the PI at the University of Kansas In preliminary work lower impedance piezoelectric composite materials that generate power for direct current DC electrical stimulation applica ...

    STTR Phase I 2016 Department of Health and Human Services
  6. Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists

    SBC: Bohemica Pharmaceuticals, LLC            Topic: 100

    DESCRIPTION provided by applicant Therapeutics based on nucleic acids NA promise to revolutionize treatment of multiple diseases but their widespread use is currently limited by the lack of efficient delivery methods We have recently developed a new NA delivery platform based on polymeric CXCR inhibitors PCX suitable as dual function systems for simultaneous NA delivery and inhibition of ...

    STTR Phase I 2016 Department of Health and Human Services
  7. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a GABA Enzyme for Biosensor and Point-of-Care Applications

    SBC: Pinnacle Technology, Inc.            Topic: 101

    DESCRIPTION provided by applicant As the most important inhibitory neurotransmitter in the brain a detailed understanding of the implications of gamma aminobutyric acid GABA release remains elusive The measurement of GABA concentrations is a difficult process Microdialysis is the current standard for GABA sampling in the brains of freely moving animals but suffers from low temporal resolu ...

    SBIR Phase I 2016 Department of Health and Human Services
  9. Ultrasensitive SERS Nano-Sensors for Pancreatic Cancer Diagnosis and Prognosis

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 103

    ABSTRACT Pancreatic cancer PC is an extremely aggressive malignancy with one of the worst prognoses of all cancers with a median survival of less than one year and an overall year survival of andlt With marked resistance to chemo and radiotherapies surgery is the only curative option In patients with localized disease and no lymph node or extra pancreatic metastases complete surgical ...

    STTR Phase I 2016 Department of Health and Human Services
  10. Development of Chol-DsiRNA Polyplexes to Improve the Therapy of Breast Cancer

    SBC: ACTORIUS PHARMACEUTICALS, LLC            Topic: 100

    DESCRIPTION provided by applicant Breast cancer is the most common type of cancer in women between the ages of and and responsible for deaths annually If treated early five year survival rates for patients in the U S are between and but drop to once metastatic breast cancer has developed Thus there is a great need to develop more effective treatment strategies fo ...

    STTR Phase I 2016 Department of Health and Human Services

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