List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of a serotype-independent vaccine based on Salmonella T3SA proteins

    SBC: INTEGRATED ANIMAL RESEARCH LLC            Topic: 83

    Salmonella is a bacteriathat causessevere stomach and gut distressinpeople andis the leading cause of food-borne illnesses resulting in hospitalization and death in the US. The resulting economic losses caused bythisbacteriain the livestock industry are staggering with much of the loss attributed to recalls, permanent disruption of the gut lining impairing nutrient absorption, and necessary cullin ...

    SBIR Phase I 2016 Department of Agriculture
  2. Enhanced Membranes for Sweetening of Manure based BioGas

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 88

    Every year over 1 billion tons of fresh animal manure is produced in US and it raises pollution concerns. "Anaerobic digestion" is an environmental friendly and energy efficient way to dispose animal manure. Animal manure is converted to biogas and digestate through this process. The animal manure digestate has a much less pollution potential than untreated animal manure and can be used as a chemi ...

    SBIR Phase I 2016 Department of Agriculture
  3. Low Cost Innovative Greener/Safer Process for Converting Cellulose to Glucose

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 81

    The current dependence of the United States on fossil fuels has sparked enormous interest in the development of biomaterials derived from biomass, specifically cellulosic biomaterials. Cellulosic biomaterials are a carbon neutral, renewable resource, and their use could drastically curtail total carbon dioxide emissions while also reducing U.S. dependence on fossil fuels. Biofuels is one example o ...

    SBIR Phase II 2016 Department of Agriculture
  4. Advancing a Glioma Immunotherapy

    SBC: IN CYTU, INC.            Topic: 102

    DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

    SBIR Phase II 2016 Department of Health and Human Services
  5. Novel SCD1 inhibitors for treatment of cancer

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    DESCRIPTION provided by applicant Metastatic clear cell renal cell carcinoma mccRCC is an incurable cancer with a year survival of less than for which novel therapeutic agents need to be developed urgently It is notoriously resistant to chemotherapy and radiation Although molecularly targeted therapies have led to an improvement in survival the benefit is rather limited due to event ...

    STTR Phase I 2016 Department of Health and Human Services
  6. Development of an Osteoinductive Spinal Fusion Implant for Enhanced Fusion Rates

    SBC: Evoke Medical, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant The objective of this Phase I STTR research is to develop and test osteoinductive lumbar spinal fusion implant prototypes made using materials technology developments discovered by the PI at the University of Kansas In preliminary work lower impedance piezoelectric composite materials that generate power for direct current DC electrical stimulation applica ...

    STTR Phase I 2016 Department of Health and Human Services
  7. A microchip to analyze trafficking leukocytes in Alzheimer’s disease patients

    SBC: IsoPlexis            Topic: NIA

    DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most common neurodegenerative diseases that lead to detrimental outcomes such as progressive memory deficit and cognitive impairment Although it is expected that the prevalence of AD will double over the next years currently no widely accepted molecular biomarkers for early detection or non invasive monitoring ...

    SBIR Phase I 2016 Department of Health and Human Services
  8. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Leveraging advanced clinical phenotyping to enhance problem lists and support value-based healthcare

    SBC: VMT, INC.            Topic: NLM

    Project Summary As United States healthcare seeks to address inconsistent quality and overwhelming cost data and technology have become central to all suggested approaches With newly available electronic health data and massive growth in processing power the hardest challenges in using clinical data are becoming clear Big data holds the potential to enable personalized patient care population ...

    SBIR Phase I 2016 Department of Health and Human Services
  10. Development of a GABA Enzyme for Biosensor and Point-of-Care Applications

    SBC: Pinnacle Technology, Inc.            Topic: 101

    DESCRIPTION provided by applicant As the most important inhibitory neurotransmitter in the brain a detailed understanding of the implications of gamma aminobutyric acid GABA release remains elusive The measurement of GABA concentrations is a difficult process Microdialysis is the current standard for GABA sampling in the brains of freely moving animals but suffers from low temporal resolu ...

    SBIR Phase I 2016 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government