Award Data

DESCRIPTION (provided by applicant): The long-term objective of this work is to design bi-functional peptide-drug conjugates that specifically target leukocytes. The peptide sequences are derived from ICAM-1 and bind to LFA-1 on activated leukocytes. The

The goal of this SBIR Phase II project is to bring the demonstrated Gallium Nitride (GaN) microdisplay technology to industrial maturity and to final commercialization levels. The project's goal will be accomplished by further optimizing the microdisplay device structural design and fabrication process based on the demonstrative results obtained in Phase I. Based on high-efficiency semiconductor m ...

DESCRIPTION (provided by applicant): More than 10 million individuals in the U.S. are thought to suffer from diabetic neuropathies. Many serious medical problems stem from this condition, including degradation of the mechanical senses of touch and propri

DESCRIPTION (provided by applicant): Stroke survivors constitute one of the largest groups of patients receiving rehabilitation services in the United States. The inability of most stroke survivors to regain full sensorimotor function significantly impacts quality of life while generating tremendous ongoing health care costs and losses to productivity. Recent scientific and clinical findings have ...

DESCRIPTION (provided by applicant): Stroke survivors constitute one of the largest groups of patients receiving rehabilitation services in the United States. The inability of most stroke survivors to regain full sensorimotor function significantly imp

Natural flavor compounds find wide applications in the food, feed, cosmetic, chemical and pharmaceutical industry, and isoamyl acetate is an important flavor ester. In this research program, a low-cost process is proposed to convert glucose from renewable sources to isoamyl acetate using a high-yielding metabolically engineered E coli. Isoamyl acetate produced via chemical synthesis results in an ...

Alaska Native Technologies, LLC (ANT) proposes to develop a hull-mounted sonar system that would be integrated into the DD(X) HF Mine Avoidance Bow Sonar processing chain to provide search and identification of small objects in the water column ±60° swaths in front of the vessel. The proposed approach will develop a dual-mode broadband sonar system, capable of operating in either wide-beam or n ...

75336-A broad category of experiments in astro-particle and high energy physics requires the construction of ultra-high-purity and ultra-low-radioactive-background, cubic-meter-scale vessels to be used as containers for ionization and scintillation media. Double-beta decay experiments, solar neutrino experiments, and dark matter searches would all benefit from this technology. Plastics are among ...

A W-band digital communications transceiver will be developed with 5 GHz instantaneous bandwidth utilizing the 71 - 76 and 81 - 86 GHz frequency spectrum recently allocated by the FCC. This project has both military and commercial applications for SATCOM and Point-to-Point digital communications using formats such as 1.25 Gbps and 10 Gbps Ethernet for extremely wideband data and video transmission ...

An X-band digital transmit module will be developed that is suitable for phased-array radar and communications applications. This proposed Phase II SBIR will combine our Phase-I X-band transmit module design with a DBF receiver that Applied Radar is developing through separate (non-SBIR) funding from AFRL. In addition, we will investigate the development of a synthesizer to provide a common LO sig ...