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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Improved Outcome Prediction In Galactosemic Newborns

    SBC: ADVANCED BREATH DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Galactosemia is a potentially lethal, but preventable, disease of newborns. In Phase I of this grant, we demonstrated that a 13C-galactose breath test could be used to assess the degree of impairment of whole body galactose oxidation in more than 90 galactosemic children with a broad spectrum of mutations in the human GALT gene that codes for galactose-l-phosph ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Improved Outcome Prediction In Galactosemic Newborns

    SBC: ADVANCED BREATH DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Galactosemia is a potentially lethal, but preventable, disease of newborns. In Phase I of this grant, we demonstrated that a 13C-galactose breath test could be used to assess the degree of impairment of whole body galactose oxidation in more than 90 galactosemic children with a broad spectrum of mutations in the human GALT gene that codes for galactose-l-phosph ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  3. Gene Expression and Diagnosis of Autoimmune Disease

    SBC: ARTHROCHIP, LLC            Topic: N/A

    DESCRIPTION (provided by the applicant): Autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, type I diabetes, and multiple sclerosis, are thought to arise from abnormalities of innate or adaptive immune responses. Autoimmune diseases are often difficult to diagnose, as the symptoms can be typical of other conditions and quite vague, such as musculoskeletal complaints ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  4. Gene Expression and Diagnosis of Diabetes

    SBC: ARTHROCHIP, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Autoimmune diseases are difficult to diagnose, as the symptoms can be typical of other conditions and quite vague. No currently available blood test accurately excludes or includes the possibility of an autoimmune disease in a subject, and a battery of tests and a period of observation are usually required. A single test that could readily distinguish between ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Eradicating Biofilms with Atmospheric Glow Plasma

    SBC: Atmospheric Glow Technologies            Topic: N/A

    DESCRIPTION (provided by applicant): Atmospheric Glow Technologies proposes a novel method of cold sterilization and biofilm destruction of medical and dental materials. The effort will use the One Atmosphere Uniform Glow Discharge Plasma (OAUGDP) technology to attack and destroy biofilms, which cause serious problems on medical and dental instruments and devices. The use of atmospheric plasma to ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  6. Eradicating Biofilms with Atmospheric Glow Plasma

    SBC: Atmospheric Glow Technologies            Topic: N/A

    DESCRIPTION (provided by applicant): Atmospheric Glow Technologies proposes a novel method of cold sterilization and biofilm destruction of medical and dental materials. The effort will use the One Atmosphere Uniform Glow Discharge Plasma (OAUGDP) technology to attack and destroy biofilms, which cause serious problems on medical and dental instruments and devices. The use of atmospheric plasma to ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  7. SNP Detection with Unlabeled, Unamplified Target DNA

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the research project is to further develop the dual hybridization diagnostic genotyping method into a multiplex assay capable of using unlabeled, unamplified DNA as the target. The feasibility of the dual hybridization method was demonstrated in Phase I using amplified targets and single fluorophore labels. All results indicate that the method will t ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Inexpensive Genetic Detection of Infectious Organisms

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the research project is to develop a very inexpensive and rapid capacitance measurement technique that can be used as a diagnostic test to identify specific infectious organisms, their resistance to antimicrobial drugs, and their pathogenicity in a clinical setting. The goal is to make the cost so low that managed health organizations would encourage ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Inexpensive Genetic Detection of Infectious Organisms

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim of the research project is to develop a very inexpensive and rapid capacitance measurement technique that can be used as a diagnostic test to identify specific infectious organisms, their resistance to antimicrobial drugs, and their pathogenicity in a clinical setting. The goal is to make the cost so low that managed health organizations would encourage ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  10. Enhancement of Cancer Therapy by Inhibiting NF-kB

    SBC: CELTEK BIOSCIENCE, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Our long-term goal is to develop a novel therapeutic treatment of human prostate cancer (PCA) by sensitizing PCA cells to apoptosis induced by tumor necrosis factor (TNF)-alpha or other cytotoxic agents. Conventional therapeutic treatments of PCA, such as surgery and chemotherapy, have received only limited success. This therapeutic deficiency has largely re ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
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