Award Data

Accurate Automation Corporation proposes a three-pronged effort to build on the Phase I program to develop technologies in support of the NASA Hyper-X program and the X-43 series of research vehicles (X-43A, X-43B, and X-43C). The data and technologies developed under the proposed Phase II program will also support the development and testing of future hypersonic vehicles and reusable launch vehic ...

DESCRIPTION (provided by applicant): Galactosemia is a potentially lethal, but preventable, disease of newborns. In Phase I of this grant, we demonstrated that a 13C-galactose breath test could be used to assess the degree of impairment of whole body galactose oxidation in more than 90 galactosemic children with a broad spectrum of mutations in the human GALT gene that codes for galactose-l-phosph ...

DESCRIPTION (provided by applicant): Atmospheric Glow Technologies proposes a novel method of cold sterilization and biofilm destruction of medical and dental materials. The effort will use the One Atmosphere Uniform Glow Discharge Plasma (OAUGDP) technology to attack and destroy biofilms, which cause serious problems on medical and dental instruments and devices. The use of atmospheric plasma to ...

DESCRIPTION (provided by applicant): The aim of the research project is to further develop the dual hybridization diagnostic genotyping method into a multiplex assay capable of using unlabeled, unamplified DNA as the target. The feasibility of the dual hybridization method was demonstrated in Phase I using amplified targets and single fluorophore labels. All results indicate that the method will t ...

DESCRIPTION (provided by applicant): The aim of the research project is to develop a very inexpensive and rapid capacitance measurement technique that can be used as a diagnostic test to identify specific infectious organisms, their resistance to antimicrobial drugs, and their pathogenicity in a clinical setting. The goal is to make the cost so low that managed health organizations would encourage ...

NON-TECHNICAL SUMMARY: Agricultural spray equipment operators typically cannot monitor all nozzles along the boom. Clogged or malfunctioning nozzles produce undesirable spraying results. This project is designed to lead directly to a useful product, namely, a single-nozzle monitoring unit for agricultural spray applications. The monitoring capabilities of the system will allow more efficient, reli ...

NON-TECHNICAL SUMMARY: Economic impacts due to coldwater disease (CWD) have dramatically increased in recent years at public and private aquaculture facilities and CWD is the number one disese problem in the commercial rainbow trout industry in Idaho. In the United States, antibiotics available for the therapeutic treatment of fish with this disease are very limited and not expected to increase. V ...

DESCRIPTION (provided by applicant): The purpose of this Phase I project is to produce and pilot test the feasibility of learner-managed professional-development packages for teachers to use to learn how to create safe, supportive learning communities in their classrooms to enable students to learn the necessary social and cognitive skills to maintain ...

Phase II will focus on the design and development of a prototype needle-free injection system for administering BChE enzyme into humans to provide protection against chemical warfare agents. The Phase I proof-of-concept demonstrated the accelerateddelivery of BChE into the circulatory system using needle-free injection. The second phase of this project will consist of the following three tasks: ...

70075T02-II Significant fuel cost savings can be realized in the automotive and aerospace industries by employing lightweight materials in the design and fabrication of vehicular components. To date, the exploitation of lightweight magnesium and aluminum alloys in component fabrication has been restricted due to their limited formability at room temperatures in conventional metal stamping proc ...