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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 39 results
 
  • Record 1 TO 39

  1. Aging Resistant Ceramics for Total Hip Arthroplasty

    SBC: SINTX TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Zirconia bio-ceramics (e.g. Prozyr) have the highest toughness and strength compared to other bio-ceramics such as alumina (e.g. Biolox) or zirconia-toughened alumina (Biolox-Delta). However, as highlighted by the recent recall of St. Gobain zirconia heads, a critical need remains to develop bio-ceramics with both significantly reduced wear characteristics and ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  2. Screening for anti-RSV compounds with indicator cells

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the cytoplasm of transfected cells. Significant advances have been made in identifying the cis-acting elem ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  3. Screening for anti-RSV compounds with indicator cells

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to use an infection-independent cell-based assay to identify compounds that inhibit respiratory syncytial virus (RSV). The basis of this bioassay is expression of a reporter gene from an artificial viral genome present within the cytoplasm of transfected cells. Significant advances have been made in identifying the cis-acting elem ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health

  4. Construction of a Respiratory Syncytial Virus Replicon

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the most important respiratory pathogen in infants, especially those born prematurely. It is also an important cause of disease in the elderly and immunosuppressed. There is no vaccine available to protect against RSV and "at risk" infants are presently treated by passive immunization. An effective small molecule drug that ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  5. Multiplexed Gene Assays by Microtiter Plate Microarrays

    SBC: APATH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The drug discovery industry is under increasing pressure to rapidly prioritize compound candidates based on their efficacy and specificity. Although traditional chip based gene expression microarrays can provide significant insights, sample format and throughput considerations preclude more widespread use. Microtiter plate based microarray (MPMA) systems can be ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  6. Ultraviolet Light Devices for Vitamin D

    SBC: APOLLO LIGHT SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Vitamin D deficiency is now recognized as a significant health problem for middle-aged and older adults. Vitamin D deficiency exacerbates osteoporosis and causes the bone disease, osteomalacia. Vitamin D deficiency increases risk of skeletal fractures. It is well known that the ultraviolet B portion of the solar spectrum is responsible for the cutaneous product ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  7. Receptor Targeted, RGD-Linked, Cytotoxic Peptides

    SBC: BIOSYNTHEMA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Somatostatin receptors are expressed on a number of tumor types including, neuroendocrine tumors, small cell lung carcinoma, and breast cancer. Commercial radiodiagnostic imaging agents targeted to this receptor are currently in clinical use, and corresponding radiotherapeutic agents are in clinical evaluation. While these therapeutic agents show much promise, ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  8. Innovative Cardiac Imaging Phantom Approach for Tc-99

    SBC: CARDIOVASCULAR IMAGING TECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): Coronary artery disease results in over one-half million deaths annually in the United States and is estimated to become the leading cause of death worldwide by the year 2020. Single Photon Emission Computed Tomography (SPECT) of the myocardium is a valuable clinical tool for the diagnosis and assessment of coronary artery disease usingT1-201 or Tc-99m-based ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  9. N/A

    SBC: COGNITECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health

  10. N/A

    SBC: COGNITECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
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