Award Data

This Small Business Innovation Research (SBIR) Phase II project proposes to develop an 840 nm spectral domain optical coherence tomography (OCT) system for intravascular imaging applications. The system will be designed to provide images equal to or better than what is currently clinically available, and will have higher imaging speeds with lower cost. Intravascular OCT is poised for clinical acce ...

The innovation of this SBIR Phase II project is the development and commercialization of a low-cost through-building surveillance product for police and SWAT teams that locates and tracks people across an entire building using a network of wireless sensors deployed around the outside of the building. Unlike other through-single-wall imaging technologies, a device does not need to be held against a ...

This Small Business Innovation Research (SBIR) Phase II project proposes to develop fungal bioinsecticides for control of bark beetles in forestry. Bark beetles are difficult to control. With a life cycle mostly under tree bark, exposure to insecticides is limited to the short period when adults search for new host trees. Control of mountain pine beetle (MPB), one of the most damaging species, is ...

This Small Business Innovation Research Phase II project will develop targeted nanoparticle delivery systems capable of delivering conventional cytotoxics preferentially to tumor cells. While therapeutic nanoparticles have been introduced into clinical practice (Abraxane(TM) and Doxil(TM)) and others are in development, none have been developed that show tumor target specificity (as opposed to inc ...

This Small Business Innovation Research (SBIR) Phase II project will adapt a photonics based signal processor to propel applications in extreme bandwidth spread-spectrum wireless communications. The signal processor prototype known as the spatial spectral holographic (S2H) extreme bandwidth analyzer / correlator (EBAC) will function as a correlating receiver for low probability of intercept (cover ...

The innovation combines mobile technologies becoming more widely used in schools, an evidence-based beginning reading program with a long history of R & D and widespread use in many settings, ongoing student progress monitoring and assessment with results and instructional recommendations delivered in real time, and instructional supports that assist teachers, paraprofessionals, tutors, and parent ...

This Small Business Innovation Research (SBIR) Phase II project will advance the technology research and development necessary to bring wireless instrumentation and smartphone technology used for feedback to lower-limb amputees about their real-time performance, for rehabilitation in situ. The intellectual merit of the proposed research lies in the opportunity to transform the field of rehabilitat ...

This Small Business Innovation Research (SBIR) Phase I project will establish the feasibility of developing a genetically-encoded biosensor to monitor levels of cyclic adenosine monophosphate (cAMP), an important second messenger component of drug signaling pathways. Unlike existing FRET-based biosensors that depend upon energy transfer between two fluorescent molecules, this sensor will employ a ...

This Small Business Innovation Research (SBIR) Phase I will focus on development of novel biopolymers obtained by covalently attaching peptide side chains to hyaluronic acid (HA) backbone polymer chains through carefully controlled chemistry. The resulting material can be used for soft tissue augmentation, protection, and rejuvenation. The work will rely on a combined experimental and molecular mo ...

This Small Business Innovation Research Phase I project describes a simple, novel and economical process for converting lignocellulosic feedstocks, such as wheat straw, to lipids for conversion to biodiesel and fatty acids for specialty markets (e.g. wax esters, stearic/oleic acids) using a minimal number of steps compared to current technologies. The innovative technology described here is based ...