Award Data

This Phase I SBIR project is directed at developing a portable, sensitive, and affordable device to detect M. tuberculosis (Mtb) in sputum samples and simultaneously determine the multidrug resistance profile of the pathogen, all within 3 days of sputum collection (It takes more than 6 weeks using current technology). By significantly reducing the time to detect viable Mtb and obtain its drug resi ...

This SBIR Phase I project will benefit society by reducing the cost of manufacturing biologic pharmaceuticals and improving their quality, including pharmaceuticals that are currently too costly to manufacture because they target relatively small patient populations. The proposed innovation will advance state-of-the-art by providing a continuous in-situ multi-analyte sensor enabling novel methods ...

This SBIR phase I project seeks to address the critical need for lung cancer diagnosis at an early stage. North America has the highest age-standardized incidence of lung cancer in the world. An estimated 224,390 new cases of lung cancer will be diagnosed this year and 158,080 deaths are predicted to occur due to lung cancer in 2016. The five-year survival rate for lung cancer patients is much low ...

This Small Business Technology Transfer Phase I project will develop advanced tools for semiconductor metrology that are essential for high accuracy at finer resolution as progress continues to the finer lithography nodes. This progress is essential to satisfy the demand for greater performance in numerous consumer products as well as many other applications. The intellectual merit of this project ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will benefit nearly 6 million children per year who are suspected of having abnormal Gastroesophageal Reflux (GER) which can lead to a more serious condition with numerous complications referred to as Gastroesophageal Reflux Disease (GERD). Current detection paradigms include costly and invasi ...

This project will develop a multi-sensory therapy program for children diagnosed with Autism Spectrum Disorder by improving eye contact. Children with Autism Spectrum Disorder do not make eye contact readily and eye contact is a key component in progressing social behavior. Current methodologies to assist these children in maximizing their capabilities are out of reach for many, costing families t ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to develop natural alternatives to synthetic chemicals that are used to impart color to food, medicine, and cosmetics. Negative health impacts of some high volume synthetic colorants are driving demand for natural and safe colorants that are obtained from biological sources. This proj ...

This Small Business Innovation Research Phase II project aims to develop copper based pastes for the metallization of silicon solar cells. Photovoltaics (PV) offer an opportunity for clean and affordable energy and over the past decade the PV industry has seen annual compound growth rates of over 50%. Although revenues are high, the profit margins for many manufacturers have substantially diminish ...

This SBIR Phase I project will determine the feasibility of a new high risk technology for treatment of age-related macular degeneration (AMD). The technology is an AAV2-mediated concurrent expression of recombinant proteins to intracellularly suppress the critical growth factors VEGF-A (vascular endothelial growth factor A) and PDGF-B (platelet-derived growth factor) in a single injection. AMD is ...

The broader impact/commercial potential of this project consists of providing a new means for visually impaired people to understand information via haptics. In order to accomplish this, the company is creating micro actuators and refreshing displays that will permit the blind to understand visual information quickly. One major potential societal benefit will be directly related to visually impair ...